2'-氨基-4-联苯基羧酸合成路线 （共 8 条）
反应条件
potassium peroxymonosulfate; sodium hydrogencarbonate in hexane; water; acetone T=0°C; 6.66667 h;
参考文献
SIENA BIOTECH S.P.A.
Patent: WO2006/8133 A2, 2006 ;
Location in patent: Page/Page column 21 ;
WO 2006/008133 A2
反应条件
1: With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; acetonitrile
T=90°C; 15 - 20 h;
2: With hydrogenchloride in water
参考文献
SIENA BIOTECH S.P.A.
Patent: WO2006/8133 A2, 2006 ;
Location in patent: Page/Page column 19-20 ;
WO 2006/008133 A2
反应条件
ammonium hydroxide; iron(II) sulfate
参考文献
Campbell
Journal of the Chemical Society, 1950 , p. 3109,3113
反应条件
1: acetic acid; paraformaldehyde; ZnCl2; HCl
2: Na2Cr2O7; aqueous H2SO4
3: FeSO4; aqueous NH3
View Scheme
参考文献
Campbell
Journal of the Chemical Society, 1950 , p. 3109,3113
反应条件
potassium hydroxide in methanol
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
1: aq. NaOBr / dioxane
2: (i) SOCl2, (ii) /BRN= 1098229/
3: Fe, aq. HCl / methanol
4: aq. KOH / methanol
View Scheme
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
1: Na2Cr2O7; aqueous H2SO4
2: FeSO4; aqueous NH3
View Scheme
参考文献
Campbell
Journal of the Chemical Society, 1950 , p. 3109,3113
反应条件
(i) (diazotization), (ii) (hydrolysis), (iii) /BRN= 1098229/, HCl; Multistep reaction;
参考文献
Oki,M.; Iwamura,H.
Bulletin of the Chemical Society of Japan, 1961 , vol. 34, p. 1395 - 1401
