3-(2,5二氧-吡咯啉-1-基)-丙酸合成路线 （共 5 条）
反应条件
acetic acid 10 h; Heating;
参考文献
Khadilkar, B M; Bhayade, S R
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 3 p. 338 - 342
反应条件
sodium hydroxide; potassium permanganate; water
参考文献
Journal of the American Chemical Society, , vol. 71, p. 1251
反应条件
sodium hydroxide; water
参考文献
Journal of the American Chemical Society, , vol. 74, p. 1323
反应条件
triethylamine in toluene Condensation; 4 h; Heating;
参考文献
Acta Crystallographica Section C: Crystal Structure Communications, , vol. 55, # 9 p. 1427 - 1429
反应条件
1: Et3N / tetrahydrofuran / 1 h / 0 °C
2: tetrahydrofuran; toluene / 17 h / Ambient temperature
3: NaI / acetic acid / 3 h / Heating
4: Na, CH3OH / 0.08 h
5: 61 percent / xylene / 168 h / Heating
6: 1.) SnCl4 / 1.) CH2Cl2, -78 deg C, 15 min 2.) 20 h, room temp.
7: LiAlH4 / tetrahydrofuran / 24 h / Ambient temperature
8: pyridinium chlorochromate / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Flitsch, Wilhelm; Pandl, Klaus
Liebigs Annalen der Chemie, 1987 , p. 649 - 654
