2-溴-1,3-二异丙基苯合成路线 （共 11 条）
反应条件
bromine; triphenylphosphine in acetonitrile
参考文献
E. I. Du Pont de Nemours and Company
Patent: US3962307 A1, 1976 ;
反应条件
hydrogen bromide; sodium nitrite
T=-50°C; 1 h;
参考文献
Wallasch, Mark W.; Weismann, Daniel; Riehn, Christoph; Ambras, Stefan; Wolmershaeuser, Gotthelf; Lagutschenkov, Anita; Niedner-Schatteburg, Gereon; Sitzmann, Helmut
Organometallics, 2010 , vol. 29, # 4 p. 806 - 813
反应条件
tetrachloromethane; bromine; iron
T=0°C; unter Lichtausschluss;
参考文献
Newton
Journal of the American Chemical Society, 1943 , vol. 65, p. 2444
反应条件
trichloromonobromomethane; isopentyl nitrite in ethylene glycol dimethyl ether
T=75°C; 14 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Knorr, Rudolf; Ruhdorfer, Jakob; Boehrer, Petra; Bronberger, Hildegard; Raepple, Edith
Liebigs Annalen der Chemie, 1994 , # 4 p. 433 - 438
反应条件
T=0°C; unter Lichtausschluss;
参考文献
Newton
Journal of the American Chemical Society, 1943 , vol. 65, p. 2444
反应条件
1: (i) Mg, (ii) /BRN= 1900390/
2: SOCl2
View Scheme
参考文献
Fleurke,K.H. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1962 , vol. 81, p. 93 - 101
参考文献
Warner-Lambert Company
Patent: US5807846 A1, 1998 ;
反应条件
(i) Mg, (ii) /BRN= 1900390/; Multistep reaction;
参考文献
Goetz-Schatowitz, P.-R.; Struth, G.; Voss, J.; Wiegand, G.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1993 , vol. 335, # 3 p. 230 - 234
反应条件
1: (i) Mg, (ii) /BRN= 1900390/
2: (esterification)
3: LiAlH4
View Scheme
参考文献
van Zanten,B.; Nauta,W.
Recueil des Travaux Chimiques des Pays-Bas, 1960 , vol. 79, p. 1211 - 1222
反应条件
sodium t-butanolate; (1,1'-bis(di-tert-butylphosphino)ferrocene)PdCl2 in tetrahydrofuran
T=20°C;
参考文献
Grasa, Gabriela A.; Colacot, Thomas J.
Organic Process Research and Development, 2008 , vol. 12, # 3 p. 522 - 529
