N-(4-氨基-3-甲氧基苯基)甲磺酰胺合成路线 （共 18 条）
反应条件
hydrogen; palladium on activated charcoal in methanol P=1520 Torr; 0.25 h;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 4 p. 652 - 658
反应条件
hydrogenchloride in ethanol; water reflux, 5 h; 25 deg C, overnight;
参考文献
Brennan; Colbry; Leeds; Leja; Priebe; Reily; Showalter; Uhlendorf; Atwell; Denny
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 5 p. 1469 - 1476
反应条件
sodium hydroxide Hydrolysis; Heating;
参考文献
Ferlin, Maria Grazia; Marzano, Cristina; Chiarelotto, Gianfranco; Baccichetti, Francarosa; Bordin, Franco
European Journal of Medicinal Chemistry, 2000 , vol. 35, # 9 p. 827 - 837
反应条件
1: 95 percent / tetrahydrofuran / Heating 2: 90 percent / H2 / palladium on carbon 3: 75 percent / pyridine 4: 94 percent / aq. NaOH / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 35, # 9 p. 827 - 837
反应条件
1: pyridine / 4 h / 20 °C 2: H2 / Pd/C / methanol / 0.25 h / 1520 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 4 p. 652 - 658
反应条件
1: 4N aq. HCl / ethanol / 3 h / Heating 2: pyridine / 4 h / 20 °C 3: H2 / Pd/C / methanol / 0.25 h / 1520 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 4 p. 652 - 658
反应条件
1: H2 / Raney nickel / methanol / 22.5 h / 2585.7 Torr 2: pyridine / CH2Cl2 / 25 °C 3: 82 percent / conc. HCl / ethanol; H2O / reflux, 5 h; 25 deg C, overnight View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 26, # 5 p. 1469 - 1476
反应条件
1: 90 percent / H2 / palladium on carbon 2: 75 percent / pyridine 3: 94 percent / aq. NaOH / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 35, # 9 p. 827 - 837
反应条件
1: pyridine / CH2Cl2 / 25 °C 2: 82 percent / conc. HCl / ethanol; H2O / reflux, 5 h; 25 deg C, overnight View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 26, # 5 p. 1469 - 1476
反应条件
1: 75 percent / pyridine 2: 94 percent / aq. NaOH / Heating View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 35, # 9 p. 827 - 837
