(9ci)-1-甲基-7-硝基-1H-苯并咪唑合成路线 （共 7 条）
反应条件
palladium 10 on activated carbon; hydrogen in ethanol
参考文献
Garcia, M. Angeles; Claramunt, Rosa M.; Solcan, Tomas; Milata, Viktor; Alkorta, Ibon; Elguero, Jose
Magnetic Resonance in Chemistry, 2009 , vol. 47, # 2 p. 100 - 104
反应条件
1: 7-nitro-1H-benzo[d]imidazole With triethylamine; benzenesulfonyl chloride in acetonitrile
8 h; Inert atmosphere;
2: methyl trifluoromethanesulfonate in acetonitrile
24 h; Inert atmosphere;
3: With N-methyl-N-butylamine in acetonitrile
T=80°C; Inert atmosphereHeating; regioselective reaction;
参考文献
Van Den Berge, Emilie; Robiette, Raphael
Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 12220 - 12223
反应条件
1: 88 percent / TBD, DMAP / 80 °C
2: 1.) quaternization; 2.) deprotection
View Scheme
参考文献
Horvath, Andras
Tetrahedron Letters, 1996 , vol. 37, # 25 p. 4423 - 4426
反应条件
1: methanol; Na2S; NaHCO3 / reagens 4:Wasser
View Scheme
参考文献
Leandri et al.
Gazzetta Chimica Italiana, 1955 , vol. 85, p. 769,788
参考文献
Leandri et al.
Gazzetta Chimica Italiana, 1955 , vol. 85, p. 769,788
反应条件
1.) quaternization; 2.) deprotection; Yield given. Multistep reaction;
参考文献
Horvath, Andras
Tetrahedron Letters, 1996 , vol. 37, # 25 p. 4423 - 4426
参考文献
Leandri et al.
Gazzetta Chimica Italiana, 1955 , vol. 85, p. 769,788
