5-氯-4-硝基-2,1,3-苯噁二唑合成路线 （共 14 条）
反应条件
1: (i) (diazotization), (ii) NaN3
2: acetic acid
3: P(OEt)3 / ethanol
4: H2SO4, HNO3
View Scheme
参考文献
Boulton,A.J. et al.
Journal of the Chemical Society, 1965 , p. 5958 - 5964
参考文献
Ghosh,P.B.; Whitehouse,M.W.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 2 p. 305 - 311
反应条件
1: 28 percent / fuming HNO3, conc. H2SO4 / a) RT, 2 h, b) 95 deg C, 1 h
2: 82 percent / CH2Cl2 / 0.17 h / Ambient temperature
View Scheme
参考文献
Read, Roger W.; Norris, William P.
Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 435 - 445
反应条件
sulfuric acid; nitric acid
a) RT, 2 h, b) 95 deg C, 1 h;
参考文献
Read, Roger W.; Norris, William P.
Australian Journal of Chemistry, 1985 , vol. 38, # 3 p. 435 - 445
