(S)-(-)-3-环己烯甲酸合成路线 （共 18 条）
反应条件
hydrogenchloride in water; ethyl acetate
参考文献
Bioorganic and Medicinal Chemistry, , vol. 17, # 3 p. 1193 - 1206
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran; water T=0°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 31, # 35 p. 5015 - 5018
反应条件
lithium hydroxide in tetrahydrofuran; water
参考文献
Tetrahedron Letters, , vol. 26, # 26 p. 3095 - 3098
参考文献
Journal of the American Chemical Society, , vol. 94, # 11 p. 3833 - 3844
Acta Chemica Scandinavica (1947-1973), , vol. 24, # 8 p. 2693 - 2698
反应条件
phosphate buffer; pig liver esterase T=20°C; pH=7.00; 4 h; Enzymatic reaction;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 13 p. 2057 - 2060
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; 5 h;
参考文献
Tetrahedron Letters, , vol. 48, # 22 p. 3829 - 3833
反应条件
dipyridinium dichromate in N,N-dimethyl-formamide 16 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 54, # 9 p. 2209 - 2216
反应条件
1: hydrogenchloride / water / 6 h / 20 °C / Reflux 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 18 h / 20 - 120 °C 3: sodium hydroxide; water / methanol / 16 h / 20 °C 4: water; acetone / 23 h / 10 - 50 °C 5: hydrogenchloride / water; tert-butyl methyl ether / 1 h / 20 °C / pH 1 View Scheme
参考文献
EP2368870 A1, ;
EP 2368870 A1
反应条件
lithium hydroxide in tetrahydrofuran; water Ambient temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 2 p. 387 - 391
反应条件
1: 1) Mg, CCl4 / 1) 0 deg C 2: LiOH*1H2O / tetrahydrofuran; H2O / Ambient temperature View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 2 p. 387 - 391
