2-羟基-1-(4-羟基苯基)乙酮合成路线 （共 10 条）
反应条件
recombinant 2,4'-dihydroxyacetophenone dioxygenase from Burkholderia sp. AZ11; oxygen T=25°C; pH=7; aq. phosphate bufferEnzymatic reaction; Kinetics; Concentration;
参考文献
Enya, Mayu; Aoyagi, Keiko; Hishikawa, Yoshihiro; Yoshimura, Azusa; Mitsukura, Koichi; Maruyama, Kiyofumi
Bioscience, Biotechnology and Biochemistry, 2012 , vol. 76, # 3 p. 567 - 574
反应条件
potassium carbonate in N,N-dimethyl-formamide T=0 - 10°C; 10 h; Inert atmosphere;
参考文献
Ren, Xuhong; Wang, Jingjing; Shen, Liu-Lan; Li, Wei; Muraoka, Osamu; Cheng, Maosheng
Chemistry Letters, 2011 , vol. 40, # 10 p. 1135 - 1137
反应条件
potassium phosphate buffer; thiamine diphosphate; magnesium sulfate; benzaldehyde lyase from Pseudomonas fluorescens in dimethyl sulfoxide
T=37°C; pH=7.0; 96 h; Enzymatic reaction;
参考文献
Demir, Ayhan S.; Ayhan, Peruze; Igdir, A. Cigdem; Duygu, A. Nese
Tetrahedron, 2004 , vol. 60, # 31 p. 6509 - 6512
反应条件
sodium hydroxide in methanol
0.25 h; Ambient temperature;
参考文献
Zhang, Kai; Corrie, John E. T.; Munasinghe, V. Ranjit N.; Wan, Peter
Journal of the American Chemical Society, 1999 , vol. 121, # 24 p. 5625 - 5632
反应条件
1: DBU / benzene / 0 °C
2: 0.35 g / sodium hydroxide / methanol / 1 h / 20 °C
View Scheme
参考文献
Park, Chan-Ho; Givens, Richard S.
Journal of the American Chemical Society, 1997 , vol. 119, # 10 p. 2453 - 2463
反应条件
1: 47 percent / CuBr / ethyl acetate; CHCl3 / Heating
2: DBU / CH2Cl2
3: NaOH / methanol
View Scheme
参考文献
Givens; Jung; Park; Weber; Bartlett
Journal of the American Chemical Society, 1997 , vol. 119, # 35 p. 8369 - 8370
反应条件
1: 50 percent / Et3N / acetonitrile / 3 h / Heating
2: 67 percent / 0.5 M aq. NaOH / methanol / 0.25 h / Ambient temperature
View Scheme
参考文献
Zhang, Kai; Corrie, John E. T.; Munasinghe, V. Ranjit N.; Wan, Peter
Journal of the American Chemical Society, 1999 , vol. 121, # 24 p. 5625 - 5632
反应条件
1: TFA
2: H2O / 25 °C / Irradiation; buffer
View Scheme
参考文献
Givens; Jung; Park; Weber; Bartlett
Journal of the American Chemical Society, 1997 , vol. 119, # 35 p. 8369 - 8370
反应条件
in water
T=25°C; Irradiationbuffer; Yields of byproduct given;
参考文献
Givens; Jung; Park; Weber; Bartlett
Journal of the American Chemical Society, 1997 , vol. 119, # 35 p. 8369 - 8370
反应条件
recombinant 2,4'-dihydroxyacetophenone dioxygenase from Burkholderia sp. AZ11; oxygen
T=25°C; pH=7; aq. phosphate bufferEnzymatic reaction; Kinetics; Concentration;
参考文献
Enya, Mayu; Aoyagi, Keiko; Hishikawa, Yoshihiro; Yoshimura, Azusa; Mitsukura, Koichi; Maruyama, Kiyofumi
Bioscience, Biotechnology and Biochemistry, 2012 , vol. 76, # 3 p. 567 - 574
