1.1: 95 percent / K2CO3 / acetone / 6 h / Heating 2.1: 90 percent / 24 h / 180 °C 3.1: 95 percent / KOH / methanol / 10 h / Heating 4.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating 5.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C 5.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C View Scheme

1.1: 95 percent / KOH / methanol / 10 h / Heating 2.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating 3.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C 3.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C View Scheme

1.1: 90 percent / 24 h / 180 °C 2.1: 95 percent / KOH / methanol / 10 h / Heating 3.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating 4.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C 4.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C View Scheme

1.1: 80 percent / zinc amalgam; HCl / ethanol / 3 h / Heating 2.1: 95 percent / K2CO3 / acetone / 6 h / Heating 3.1: 90 percent / 24 h / 180 °C 4.1: 95 percent / KOH / methanol / 10 h / Heating 5.1: 96 percent / sodium hydroxyde / H2O / 1 h / Heating 6.1: NaHCO3; ozone / methanol; CH2Cl2 / 0.22 h / -70 °C 6.2: 80 percent / dimethyl sulfide / methanol; CH2Cl2 / 8 h / 20 °C View Scheme

sodium hydroxide

potassium carbonate 2) DMF, 75 deg C, 4h; Multistep reaction;

1: water; potassium permanganate 2: aqueous hydrochloric acid View Scheme

1: permanganate 2: SOCl2, pyridine / 19 h / Ambient temperature 3: 2) SOCl2 / 1) CH2Cl2, 1h, RT, 2) CH2Cl2, RT, 1h View Scheme

1: permanganate 2: SOCl2, pyridine / 19 h / Ambient temperature View Scheme

permanganate(VII) ion