5-羟基-1H-咪唑-4-甲酰胺合成路线 （共 17 条）
反应条件
sodium hydrogencarbonate in water; acetone Product distribution / selectivity;
参考文献
MBR Co., Ltd.; Kato, Nobuo
Patent: EP2196460 A1, 2010 ;
Location in patent: Page/Page column 7; 8 ;
反应条件
formic acid in ethanol T=80°C; sealed tube; Product distribution / selectivity;
参考文献
EP2196460 A1, ;
Page/Page column 6 ;
反应条件
hydrogenchloride in water T=5°C;
参考文献
Miller, Charles S.; Gurin, Samuel; Wilson, D. Wright
Journal of the American Chemical Society, 1952 , vol. 74, # 11 p. 2892 - 2894
反应条件
in water T=20°C; IrradiationpH 2-6;
参考文献
Journal of Pharmacy and Pharmacology, , vol. 33, # 12 p. 808 - 811
反应条件
in pyridine
T=41 - 43°C; 3.5 h;
参考文献
Tarumi; Takebayashi; Moriguchi; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 7 p. 1425 - 1433
参考文献
Sumitomo Chemical Company, Limited
Patent: US4317825 A1, 1982 ;
反应条件
in pyridine
T=41 - 43°C; 3.5 h; quantitative yield; Yield given;
参考文献
Tarumi; Takebayashi; Moriguchi; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 7 p. 1425 - 1433
反应条件
in methanol; diethyl ether; water
1 h; Ambient temperature;
参考文献
Tarumi; Takebayashi; Moriguchi; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 7 p. 1425 - 1433
反应条件
in methanol; diethyl ether; water
1 h; Ambient temperature;
参考文献
Tarumi; Takebayashi; Moriguchi; et al.
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 7 p. 1425 - 1433
反应条件
bis(tri-n-butyltin)oxide
1) toluene, reflux, 2 h; 2) reflux, 6 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tarumi; Atsumi
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 4 p. 875 - 885
