吡啶-2-基(吡啶-4-基)甲酮合成路线 (共 7 条)
反应条件
1: 2-bromo-pyridine With n-butyllithium in diethyl ether; hexane T=-50°C; 0.5 h; 2: 4-pyridinecarboxylic acid methyl ester in diethyl ether; hexane T=-90 - -20°C; 3.5 h;
参考文献
Chen, Xu-Dong; Mak, Thomas C. W.
Chemical Communications, 2005 , # 28 p. 3529 - 3531
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 70, p. 1054,1061
Journal of Organic Chemistry, , vol. 19, p. 1127,1129
反应条件
1: diethyl ether / -75 °C 2: diethyl ether View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1003,1015
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1003,1015
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1003,1015
反应条件
in tetrahydrofuran 1 h; Inert atmosphere;
参考文献
Rao, G. Venkateswara; Swamy, B. Narayana; Kumar, P. Hareesh; Reddy, G. Chandrasekara
Synthetic Communications, 2009 , vol. 39, # 10 p. 1835 - 1846
反应条件
hydroxylamine hydrochloride; sodium hydroxide in ethanol; water
Reflux;
参考文献
Argyle, Victoria J.; Woods, Laura M.; Roxburgh, Marina; Hanton, Lyall R.
CrystEngComm, 2013 , vol. 15, # 1 p. 120 - 134