1: tert-butyl-(2,4-dichloro-phenoxy)-dimethyl-silane With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: N,N-dimethyl-formamide in tetrahydrofuran; hexane
1 h;
3: With hydrogenchloride; water in tetrahydrofuran; hexane
T=20°C;
参考文献
PLEXXIKON, INC.
Patent: WO2008/80001 A2, 2008 ;
Location in patent: Page/Page column 75 ;
1: 2,4-dichlorotriisopropylsilyloxybenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.75 h;
2: N,N-dimethyl-formamide in tetrahydrofuran; hexane
T=-68 - -10°C;
3: With hydrogenchloride; sodium chloride
Title compound not separated from byproducts;
参考文献
Von Hirschheydt, Thomas; Voss, Edgar
Synthesis, 2004 , # 12 p. 2062 - 2065
