6-甲氧基-2,3,4,5-四氢吡啶合成路线 （共 29 条）
反应条件
in diethyl ether T=-24°C; 12 h;
参考文献
Zezza, Charles A.; Smith, Michael B.; Ross, Betsy A.; Arhin, Akwasi; Cronin, Patricia L. E.
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4397 - 4399
反应条件
anhydrous butyl ether
参考文献
Cervinka
Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 1146,1148
Chemicke Listy, 1958 , vol. 52, p. 1145
参考文献
Perrin, Charles L.; Nunez, Oswaldo
Journal of the American Chemical Society, 1986 , vol. 108, # 19 p. 5997 - 6003
反应条件
1.1: t-BuLi / hexane; tetrahydrofuran / 0.25 h / -78 - 0 °C 1.2: 68 percent / hexane; tetrahydrofuran / -78 - 20 °C 2.1: 81 percent / aq. HCl / CHCl3 3.1: 91 percent / aq. K2CO3 / methanol / 24 h View Scheme
参考文献
Taylor, Piers J. M.; Bull, Steven D.; Andrews, Philip C.
Synlett, 2006 , # 9 p. 1347 - 1350
反应条件
in N,N-dimethyl-formamide 2 h; Heating; Yields of byproduct given;
参考文献
Dunn; Kinnear; Norrie
Zeitschrift fur Chemie, 1986 , vol. 26, # 8 p. 290 - 292
反应条件
in methanol
T=20 - 25°C; 10 h;
参考文献
Granik, V. G.; Shvarts, G. Ya.; Grizik, S. I.; Tugusheva, N. Z.; Faermark, I. F.; et al.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 12 p. 842 - 847
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 12 p. 1428 - 1433
参考文献
Petersen; Tietze
Chemische Berichte, 1957 , vol. 90, p. 909,818
反应条件
in toluene
2 h; Heating;
参考文献
Dunn, A. D.; Kinnear, K. I.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 53 - 57
反应条件
in diethyl ether
T=-24°C; 12 h;
参考文献
Zezza, Charles A.; Smith, Michael B.; Ross, Betsy A.; Arhin, Akwasi; Cronin, Patricia L. E.
Journal of Organic Chemistry, 1984 , vol. 49, # 23 p. 4397 - 4399
反应条件
piperidine; triethylamine in benzene
24 h; Heating;
参考文献
Cheng; Zhao; Wang; Huang
Synthetic Communications, 1995 , vol. 25, # 9 p. 1339 - 1351
