3-氨基-3-(4-甲氧基苯基)丙酸合成路线 （共 19 条）
反应条件
ammonium acetate in ethanol T=75 - 80°C; 8 h;
参考文献
EP1621529 A1, ;
Page/Page column 40 ;
反应条件
ammonium acetate; malonic acid in ethyl alcohol water
反应条件
ammonium acetate in ethanol 6 h; Heating;
参考文献
Tetrahedron, , vol. 58, # 37 p. 7449 - 7461
反应条件
methanol; hydroxylamine
参考文献
Justus Liebigs Annalen der Chemie, , vol. 389, p. 36,111
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Synthetic Communications, , vol. 9, p. 705 - 712
反应条件
ethanol; trans-4-methoxycinnamic acid
参考文献
Journal of the American Chemical Society, , vol. 58, p. 299,301
反应条件
ammonium acetate; malonic acid in ethanol 24 h; Heating;
参考文献
Tetrahedron, , vol. 58, # 37 p. 7449 - 7461
反应条件
1: 88 percent / Na; t-BuOH / tetrahydrofuran / 0 - 20 °C 2: 51 percent / aq. HCl / Heating View Scheme
参考文献
Tetrahedron, , vol. 57, # 4 p. 703 - 712
反应条件
hydrogenchloride; aluminum amalgam 1.) THF, H2O, 1 h, 2.) EtOAc, H2O, 20 min; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 49, # 48 p. 11329 - 11340
反应条件
1: 125 - 130 °C 2: alcoholic ammonia View Scheme
参考文献
Archiv der Pharmazie (Weinheim, Germany), , p. 119
