(R)-(-)-2-氯-1-苯乙醇合成路线 （共 34 条）
参考文献
Journal of Organic Chemistry, , vol. 53, # 26 p. 6130 - 6133
Journal of the American Chemical Society, , vol. 119, # 6 p. 1492 - 1493
反应条件
Tris-HCl buffer T=30°C; pH=7.5; 24 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 74, # 4 p. 1730 - 1732
反应条件
1: With isopropyl alcohol T=30°C; 4 h; aq. bufferEnzymatic reaction; 2: With Agrobacterium radiobacter AD1 halohydrin dehalogenase HheC T=30°C; 20 h; aq. bufferEnzymatic reaction; stereoselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 4 p. 483 - 488
反应条件
in water hydrolysis by a Rhizopus nigricans culture; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 22, # 27 p. 2527 - 2530
反应条件
water; silica gel; lithium chloride 168 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Kotsuki, Hiyoshizo; Shimanouchi, Tomoyasu; Ohshima, Reiji; Fujiwara, Shunsuke
Tetrahedron, 1998 , vol. 54, # 12 p. 2709 - 2722
反应条件
Pseudomonas sp. lipase in toluene T=60°C; 5 h; Enzymatic reaction; Product distribution; Further Variations:Reagents;
参考文献
Pamies, Oscar; Baeckvall, Jan-E.
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 9006 - 9010
反应条件
N-benzyl-N,N,N-triethylammonium chloride in N,N-dimethyl-formamide T=70 - 80°C; 6 h; stereochemistry investigated; also in the presence of water or BF3*OEt2; Product distribution;
参考文献
Acta Chemica Scandinavica, , vol. 50, # 9 p. 832 - 841
反应条件
Lactobacillus brevis dehydrogenase; NADPH; tris(hydroxymethyl)methylamine hydrochloride in water; dimethyl sulfoxide T=30°C; Enzymatic reaction; Kinetics;
参考文献
Chemistry - A European Journal, , vol. 16, # 36 p. 11012 - 11019
反应条件
sodium hydroxide in diethyl ether Ambient temperature; Yield given;
参考文献
Rama Rao; Gurjar; Kaiwar
Tetrahedron Asymmetry, 1992 , vol. 3, # 7 p. 859 - 862
反应条件
1: 85 percent / NaN3 / dimethylformamide / 8 h / 100 °C 2: H2 / Pd/CaCO3 / ethyl acetate / 7 h / 25 °C / 2327.2 Torr View Scheme
参考文献
Boden, P. R.; Eden, J. M.; Higginbottom, M.; Hill, D. R.; Horwell, D. C.; et al.
European Journal of Medicinal Chemistry, 1993 , vol. 28, # 1 p. 47 - 61
