3,3-四亚甲基戊二酸酐合成路线 （共 10 条）
反应条件
acetic anhydride; acetyl chloride
参考文献
Journal of the Chemical Society, , vol. 115, p. 702
反应条件
1: NaOH-solution 2: 169 °C 3: acetic acid anhydride; acetyl chloride View Scheme
参考文献
Journal of the Chemical Society, , vol. 115, p. 702
反应条件
1: 169 °C 2: acetic acid anhydride; acetyl chloride View Scheme
参考文献
Journal of the Chemical Society, , vol. 115, p. 702
反应条件
1: With pyridine Heating; 2: With pyridine; thionyl chloride in benzene T=60°C;
参考文献
Konkel, Michael J.; Wetzel, John M.; Cahir, Marie; Craig, Douglas A.; Noble, Stewart A.; Gluchowski, Charles
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 3076 - 3079
反应条件
in toluene 10 h; Heating;
参考文献
Yevich, J. P.; Temple, D. L.; New, J. S.; Taylor, Duncan P.; Riblet, L. A.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 194 - 203
反应条件
1: 92 percent / 7percent aq. NH3 / tetrahydrofuran / 190 °C 2: 100 percent / K2CO3 / acetone / Heating 3: 65 percent / CuCl2 * 2 H2O / dioxane; H2O / 1.5 h / 70 - 80 °C 4: H2 / 10percent Pd/C / tetrahydrofuran / 0.83 h / Ambient temperature View Scheme
参考文献
Ishizumi; Kojima; Antoku
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300
反应条件
1: 92 percent / 7percent aq. NH3 / tetrahydrofuran / 190 °C 2: 100 percent / K2CO3 / acetone / Heating View Scheme
参考文献
Ishizumi; Kojima; Antoku
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300
反应条件
ammonium hydroxide in tetrahydrofuran T=190°C;
参考文献
Ishizumi; Kojima; Antoku
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 9 p. 2288 - 2300
反应条件
1: 3.2 g / hydroxylamine hydrochloride, pyridine / 18 h / 80 °C 2: 3.7 g / K2CO3, NaI / acetonitrile / 6 h / 80 °C 3: 3.42 g / K2CO3, NaI / acetonitrile / 18 h / 80 °C View Scheme
参考文献
Hrib; Jurcak; Huger; Errico; Dunn
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1068 - 1072
反应条件
pyridine; hydroxylamine hydrochloride
T=80°C; 18 h;
参考文献
Hrib; Jurcak; Huger; Errico; Dunn
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1068 - 1072
