4-苯基-2-氮杂环丁酮合成路线 （共 52 条）
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran
4 h; Ambient temperature;
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
potassium hydroxide in dimethyl sulfoxide
T=20°C;
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Osborne, Steven; Mat-Zin, Ab. Rasid
Journal of the Chemical Society, Chemical Communications, 1983 , # 17 p. 959 - 960
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran
T=20°C;
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Osborne, Steven; Mat-Zin, Ab. Rasid
Journal of the Chemical Society, Chemical Communications, 1983 , # 17 p. 959 - 960
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran
6 h; Ambient temperature;
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran
16 h; Ambient temperature;
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: 75 percent / KOH, Bu4NHSO4 / tetrahydrofuran / 20 °C
2: 17 percent / liq. NH3 / 48 h / 20 °C / sealed tube
View Scheme
参考文献
Crombie, Leslie; Jones, Raymond C. F.; Osborne, Steven; Mat-Zin, Ab. Rasid
Journal of the Chemical Society, Chemical Communications, 1983 , # 17 p. 959 - 960
反应条件
1: 81 percent / KOH, Bu4NHSO4 / tetrahydrofuran / 20 °C
2: 78 percent / liq. NH3 / 120 h / 20 °C
View Scheme
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: 94 percent / KOH, Bu4NHSO4 / tetrahydrofuran / 20 °C
2: 168 h / 60 °C / sealed tube
View Scheme
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: 70 percent / KOH / dimethylsulfoxide / 20 °C
2: 58 percent / 72 h / 53 °C
View Scheme
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: 94 percent / KOH, Bu4NHSO4 / tetrahydrofuran / 20 °C
2: 85 percent / 96 h / 45 °C / sealed tube
View Scheme
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
