4-苯基-2-氮杂环丁酮合成路线 （共 52 条）
反应条件
triphenylphosphine in acetonitrile 4.5 h; Heating;
参考文献
Kobayashi, Susumu; Iimori, Takamasa; Izawa, Toshio; Ohno, Masaji
Journal of the American Chemical Society, 1981 , vol. 103, # 9 p. 2406 - 2408
反应条件
1: in diethyl ether T=25°C; 2 h; Inert atmosphere; 2: With water; sodium carbonate; sodium sulfite in diethyl ether 1 h; Cooling with ice;
参考文献
Degennaro, Leonardo; Zenzola, Marina; Trinchera, Piera; Carroccia, Laura; Giovine, Arianna; Romanazzi, Giuseppe; Falcicchio, Aurelia; Luisi, Renzo
Chemical Communications, 2014 , vol. 50, # 14 p. 1698 - 1700
反应条件
potassium hydroxide in diethyl ether; water
参考文献
ISAGRO RICERCA S.r.l.
Patent: EP718280 A2, 1996 ;
反应条件
copper; zinc in tetrahydrofuran
参考文献
Barrett, Anthony G. M.; Fenwick, Ashley; Betts, Michael J.
Journal of the Chemical Society, Chemical Communications, 1983 , # 6 p. 299 - 301
反应条件
ammonia; sodium in tetrahydrofuran T=-78°C; 0.5 h;
参考文献
Shirai, Masashi; Nishiwaki, Tarozaemon
Journal of Chemical Research, Miniprint, 1990 , # 9 p. 2018 - 2031
反应条件
potassium hydroxide; sodium sulfite in diethyl ether; chloroform 1 h;
参考文献
Begley, Michael J.; Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Osborne, Steven; Webster, Richard A. B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2027 - 2046
反应条件
1: Et3N / hexane; heptane; toluene / 0 - 20 °C 2: toluene / Heating 3: 79 percent / tris(trimethylsilyl)silane; AIBN / toluene / 2 h / 100 °C View Scheme
参考文献
Organic Letters, , vol. 2, # 8 p. 1077 - 1079
反应条件
tri-isobutyl aluminium in toluene T=80°C; 17 h; Yields of byproduct given;
参考文献
Vorbruggen; Woodward
Tetrahedron, 1993 , vol. 49, # 8 p. 1625 - 1634
反应条件
1: 1.) LiN(SiMe3)2 / 1.) THF, 0 deg C, 30 min, 2.) THF, 30 min View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 9 p. 539 - 540
反应条件
tri-isobutyl aluminium in toluene 1.) 7 deg C, 24 h, 2.) 25 deg C, 7.5 h;
参考文献
Vorbruggen; Woodward
Tetrahedron, 1993 , vol. 49, # 8 p. 1625 - 1634
