4,6-胆固醇二烯-3-酮合成路线 （共 53 条）
3464-60-6(8S,9S,10R,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-8,9,11,12,14,15,16,17-八氢环戊烯并[a]菲-3-酮
→
反应条件
(Ph)2SiH2; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) in chloroform 1 h; Ambient temperature;
参考文献
Keinan, Ehud; Greenspoon, Noam
Journal of the American Chemical Society, 1986 , vol. 108, # 23 p. 7314 - 7325
反应条件
aluminum isopropoxide; p-benozquinone in benzene Wettstein-Oppenauer oxidation; 21 h; Heating;
参考文献
Giner, Jose-Luis; Zhao, Hui
Polish Journal of Chemistry, 2006 , vol. 80, # 4 p. 605 - 609
反应条件
copper dichloride; palladium dichloride in tetrahydrofuran; N,N-dimethyl-formamide T=60°C; 98 h;
参考文献
Haynes, Richard K.; Jackson, Roy W.; Stragalinou, Anna
Australian Journal of Chemistry, 1980 , vol. 33, # 8 p. 1537 - 1544
反应条件
2 in pyridine 20 h; Ambient temperaturefurther solvents, temperatures, reagents;
参考文献
Tachibana, Yoji
Bulletin of the Chemical Society of Japan, 1986 , vol. 59, # 11 p. 3702 - 3704
反应条件
methyl allyl carbonate; tri-n-butyltin methoxide; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane in acetonitrile Heating;
参考文献
Minami, Ichiro; Takahashi, Kazuhiko; Shimizu, Isao; Kimura, Tsuneo; Tsuji, Jiro
Tetrahedron, 1986 , vol. 42, # 11 p. 2971 - 2978
反应条件
sodium hydride; triphenylphosphine in toluene T=20°C; 16 h;
参考文献
Journal of Organometallic Chemistry, , vol. 522, # 2 p. 207 - 212
→
566-91-6(8S,9S,10S,13R,14S,17R)-10,13-二甲基-17-[(2R)-6-甲基庚烷-2-基]-6,7,8,9,11,12,14,15,16,17-十氢环戊烯并[a]菲-3-酮
反应条件
lithium chloride in N,N-dimethyl-formamide 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 46, # 5 p. 954 - 963
反应条件
1-tosyloxy-1-oxo-1H-1λ5-benzo[d][1,2]iodoxol-3-one in dimethyl sulfoxide T=20°C; 20 h;
参考文献
Yusubov, Mekhman S.; Svitich, Dmitrii Yu.; Yoshimura, Akira; Nemykin, Victor N.; Zhdankin, Viktor V.
Chemical Communications, 2013 , vol. 49, # 96 p. 11269 - 11271
反应条件
N,N-dimethyl-aniline
参考文献
Journal of the American Chemical Society, , vol. 75, p. 5489
反应条件
in acetic acid T=70°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 22, # 32 p. 3075 - 3078
