呋喃并[3,4-c]吡啶-3(1H)-酮合成路线 (共 9 条)
反应条件
lithium aluminium tetrahydride in diethyl ether
3 h;
参考文献
Kuthan,J. et al.
Collection of Czechoslovak Chemical Communications, 1977 , vol. 42, p. 283 - 291
反应条件
hydrogenchloride
0.5 h; Heating; Yield given;
参考文献
Orlek, Barry S.; Blaney, Frank E.; Brown, Frank; Clark, Michael S. G.; Hadley, Michael S.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2726 - 2735
反应条件
hydrogenchloride; sodium tetrahydroborate
1) DMF, 2) reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Orlek, Barry S.; Wadsworth, Harry; Wyman, Paul; Hadley, Michael S.
Tetrahedron Letters, 1991 , vol. 32, # 9 p. 1241 - 1244
反应条件
1: 5.1 g / lithium aluminium hydride / tetrahydrofuran / 0.07 h / 0 - 2 °C
2: 1.2 g / dicyclohexylcarbodi-imide / H2O; tetrahydrofuran / 60 h / 20 °C
View Scheme
参考文献
Ashcroft, William R.; Beal, Michael G.; Joule, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 3012 - 3015
反应条件
1: sodium hydroxide, water / 1.5 h / 20 °C
2: 5.1 g / lithium aluminium hydride / tetrahydrofuran / 0.07 h / 0 - 2 °C
3: 1.2 g / dicyclohexylcarbodi-imide / H2O; tetrahydrofuran / 60 h / 20 °C
View Scheme
参考文献
Ashcroft, William R.; Beal, Michael G.; Joule, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 3012 - 3015
反应条件
(NH4)2S2O8; sulfuric acid
0.5 h; Heating;
参考文献
Sugimori, Akira; Nishijima, Masayuki; Itoh, Hiroshi
Bulletin of the Chemical Society of Japan, 1982 , vol. 55, # 9 p. 3055 - 3056
反应条件
1: aq. AgNO3 / 4 h / Heating
2: (i) aq. HCl, (ii) aq. Na2CO3, NaBH4, (iii) aq. HCl
View Scheme
参考文献
Kuthan,J. et al.
Collection of Czechoslovak Chemical Communications, 1977 , vol. 42, p. 283 - 291
反应条件
(alkaline solution);
参考文献
Queguiner,G.; Godard,A.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1969 , vol. 269, p. 1646 - 1649
反应条件
(i) aq. HCl, (ii) aq. Na2CO3, NaBH4, (iii) aq. HCl; Multistep reaction;
参考文献
Kuthan,J. et al.
Collection of Czechoslovak Chemical Communications, 1977 , vol. 42, p. 283 - 291