萘并(2,3-b)呋喃-4,9-二酮合成路线 （共 23 条）
反应条件
sulfuric acid; nitric acid; acetic anhydride T=-5°C; 3 h;
参考文献
Koyanagi; Yamamoto; Nakayama; Tanaka
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 4 p. 1289 - 1291
反应条件
1: methyl vinyl sulphone With bromine in dichloromethane
6 h; Reflux;
2: 2-hydroxynaphthalene-1,4-dione With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; dichloromethane
6.83333 h; Cooling with iceReflux;
参考文献
Zhoushan HaiZhongZhou Xinsheng Pharmaceuticals Co., Ltd.; Jiang, Zhiwei; Wang, Aijin; Li, Xian; Li, Qingrong; Hu, Hongwei; Xu, Jiali; Hu, Yuesong; Ye, Yan
Patent: US2013/150437 A1, 2013 ;
Location in patent: Paragraph 0153 ;
反应条件
3-chloro-benzenecarboperoxoic acid in dichloromethane
T=20°C; 12 h;
参考文献
Lee, Yong Rok; Kim, Byung So; Jung, Yong Ug; Koh, Wha Soo; Cha, Jin Soon; Kim, Nam Woo
Synthetic Communications, 2002 , vol. 32, # 20 p. 3099 - 3105
反应条件
ammonium cerium(IV) nitrate in water; acetonitrile
T=0 - 5°C; Oxidation; 0.25 h;
参考文献
Godbole; Ranade; Joseph; Paradkar
Synthetic Communications, 2000 , vol. 30, # 16 p. 2951 - 2960
反应条件
1: With methanol; sodium hydrogencarbonate
Hydrolysis;
2: With chromium(VI) oxide; silica gel in dichloromethane
T=20°C; Oxidation;
参考文献
Starling, Sergia M.; Raslan, Delio S.; De Oliveira, Alaide B.; Zani
Synthetic Communications, 1998 , vol. 28, # 19 p. 3567 - 3578
反应条件
toluene-4-sulfonic acid in benzene
4 h; Heating;
参考文献
Lee, Yong Rok; Kim, Byung So; Jung, Yong Ug; Koh, Wha Soo; Cha, Jin Soon; Kim, Nam Woo
Synthetic Communications, 2002 , vol. 32, # 20 p. 3099 - 3105
反应条件
1.1: sec-butyllithium; tetramethylethylenediamine / tetrahydrofuran / 1 h / -78 °C
1.2: tetrahydrofuran
1.3: 82 percent / silica gel / toluene / Heating
2.1: 100 percent / Zn; CuSO4 / aq. NH3 / 24 h / Heating
3.1: acetic acid / zinc chloride / Heating
4.1: MeOH; NaHCO3
4.2: 58 percent / CrO3; silica gel / CH2Cl2 / 20 °C
View Scheme
参考文献
Starling, Sergia M.; Raslan, Delio S.; De Oliveira, Alaide B.; Zani
Synthetic Communications, 1998 , vol. 28, # 19 p. 3567 - 3578
反应条件
1.1: 100 percent / Zn; CuSO4 / aq. NH3 / 24 h / Heating
2.1: acetic acid / zinc chloride / Heating
3.1: MeOH; NaHCO3
3.2: 58 percent / CrO3; silica gel / CH2Cl2 / 20 °C
View Scheme
参考文献
Starling, Sergia M.; Raslan, Delio S.; De Oliveira, Alaide B.; Zani
Synthetic Communications, 1998 , vol. 28, # 19 p. 3567 - 3578
反应条件
potassium iodide; potassium hydroxide in water
4 h; Reflux;
参考文献
Tseng, Chih-Hua; Lin, Chang-Sheng; Shih, Pin-Keng; Tsao, Lo-Ti; Wang, Jih-Pyang; Cheng, Chih-Mei; Tzeng, Cherng-Chyi; Chen, Yeh-Long
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6773 - 6779
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene
Dehydrogenation; 0.5 h; Heating;
参考文献
Godbole; Ranade; Joseph; Paradkar
Synthetic Communications, 2000 , vol. 30, # 16 p. 2951 - 2960
