(R)-(+)-3-苄氧基-1,2-丙二醇合成路线 （共 67 条）
反应条件
1: With di-isopropyl azodicarboxylate; triphenylphosphine in toluene T=0°C; Mitsunobu Displacement; 0.25 h; Inert atmosphere; 2: With chloro-trimethyl-silane in toluene T=20°C; Mitsunobu Displacement; 2 h; Inert atmosphere; 3: With 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane T=0°C; 6 h; Inert atmosphere;
参考文献
Dar, Abdul Rouf; Aga, Mushtaq A.; Kumar, Brijesh; Yousuf, Syed Khalid; Taneja, Subhash Chandra
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 36 p. 6195 - 6207
反应条件
1: in chloroform T=0°C; 0.5 h; 2: With potassium carbonate in methanol T=0°C; 0.333333 h; Further stages.;
参考文献
Guindon; Soucy; Yoakim; Ogilvie; Plamondon
Journal of Organic Chemistry, 2001 , vol. 66, # 26 p. 8992 - 8996
反应条件
triphenylphosphine; diethylazodicarboxylate in benzene 20 h; Heating; Yield given. Title compound not separated from byproducts;
参考文献
Gurjar; Sarma; Sadalapure; Adhikari
Synthesis, 1998 , # 10 p. 1424 - 1424
反应条件
pyridine 0 deg C, 0.5 h; r.t., 18 h;
参考文献
Baig, Mirza Hamed A.; Baskaran, Subramanian; Banerjee, Sharmila; Trivedi, Girish K.
Tetrahedron, 1995 , vol. 51, # 16 p. 4723 - 4732
反应条件
triphenylphosphine; diethylazodicarboxylate in benzene 20 h; Heating;
参考文献
Takano, Seiichi; Seya, Kazuhiko; Goto, Emiko; Hirama, Michiyasu; Ogasawara, Kunio
Synthesis, 1983 , # 2 p. 116 - 117
反应条件
triphenylphosphine; diethylazodicarboxylate in benzene 20 h; Heating; Yield given. Title compound not separated from byproducts;
参考文献
Gurjar; Sarma; Sadalapure; Adhikari
Synthesis, 1998 , # 10 p. 1424 - 1424
反应条件
hydrogen cation in acetone
参考文献
Saito, Seiki; Kuroda, Akiyoshi; Matsunaga, Hiroshi; Ikeda, Shushiro
Tetrahedron, 1996 , vol. 52, # 44 p. 13919 - 13932
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=0 - 20°C; 2.66667 h;
参考文献
Park, Jong Moon; De Castro, Kathlia A.; Ahn, Hyunseok; Rhee, Hakjune
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 9 p. 2689 - 2691
反应条件
pyridine
12 h; Ambient temperature;
参考文献
Iguchi, Kazuo; Kitade, Makoto; Kashiwagi, Toshihiko; Yamada, Yasuji
Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5690 - 5698
反应条件
1: 100 percent / pyridine / CH2Cl2 / 4 h / 0 deg C -> room temp.
2: 91 percent / acetic anhydride / 1.5 h / Heating
View Scheme
参考文献
Takano, Seiichi; Seya, Kazuhiko; Goto, Emiko; Hirama, Michiyasu; Ogasawara, Kunio
Synthesis, 1983 , # 2 p. 116 - 117
