1H-吡咯[2,3-B]吡啶-2,3-二酮合成路线 （共 13 条）
反应条件
N-bromosuccinmide; dimethyl sulfoxide T=120°C; 0.5 h;
参考文献
Cheng, Xinlai; Merz, Karl-Heinz; Vatter, Sandra; Christ, Jochen; Woelfl, Stefan; Eisenbrand, Gerhard
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 247 - 255
反应条件
AlCl3, aluminium chloride; silica gel; pyridinium chlorochromate in 1,2-dichloro-ethane T=80°C; 3 h; Inert atmosphere;
参考文献
Sriram, Rekulapally; Sesha Sai Pavan Kumar, Chebolu Naga; Raghunandan, Nerella; Ramesh, Vadla; Sarangapani, Manda; Rao, Vaidya Jayathirtha
Synthetic Communications, 2012 , vol. 42, # 23 p. 3419 - 3428
反应条件
pyridinium chlorochromate in 1,2-dichloro-ethane T=80°C; 4.5 h;
参考文献
Kumar, Chebolu Naga Sesha Sai Pavan; Devi, Chebrolu Lavanya; Rao, Vaidya Jayathirtha; Palaniappan, Srinivasan
Synlett, 2008 , # 13 p. 2023 - 2027
反应条件
N-bromosuccinmide; dimethyl sulfoxide T=80°C; 1.5 h;
参考文献
Kritsanida, Marina; Magiatis, Prokopios; Skaltsounis, Alexios-Leandros; Peng, Youyi; Li, Peng; Wennogle, Lawrence P.
Journal of Natural Products, 2009 , vol. 72, # 12 p. 2199 - 2202
反应条件
methanol; water 24 h; Heating / reflux;
参考文献
WO2005/5378 A2, ;
Page/Page column 43 ;
WO 2005/005378 A2
反应条件
selenium(IV) oxide; water in 1,4-dioxane Reflux;
参考文献
Abass, Mohamed; Mayas, Aisha S.
Journal of Chemical Research, 2009 , # 2 p. 93 - 94
反应条件
N-bromosuccinmide; dimethyl sulfoxide T=60°C; 6 h;
参考文献
Journal of Natural Products, , vol. 72, # 12 p. 2199 - 2202
反应条件
1.1: triethylamine / dichloromethane / 3 h / 0 - 20 °C 2.1: n-butyllithium / hexane; tetrahydrofuran / 4 h / -78 - -20 °C 2.2: -78 - 20 °C 3.1: hydrogenchloride / |Reflux 4.1: N-bromosuccinmide; dimethyl sulfoxide / 0.5 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 247 - 255
反应条件
1.1: n-butyllithium / hexane; tetrahydrofuran / 4 h / -78 - -20 °C 1.2: -78 - 20 °C 2.1: hydrogenchloride / |Reflux 3.1: N-bromosuccinmide; dimethyl sulfoxide / 0.5 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 22, # 1 p. 247 - 255
