2-氨基-4,5-二甲氧基苯甲酸合成路线 （共 59 条）
反应条件
1: With hydrogen; palladium 10 on activated carbon in water T=50°C; P=2625.26 Torr; pH=6.6; 2: With hydrogen; palladium 10 on activated carbon in water T=50°C; P=2625.26 Torr; pH=6.6;
参考文献
Jacobi, Albrecht; Schul, Michael
Patent: US2008/319194 A1, 2008 ;
Location in patent: Page/Page column 4 ;
反应条件
hydrogen iodide T=20°C; 2 h;
参考文献
Kamal, Ahmed; Reddy; Reddy, D.Rajasekhar
Tetrahedron Letters, 2002 , vol. 43, # 37 p. 6629 - 6631
参考文献
Journal of the American Chemical Society, , vol. 41, p. 2147
反应条件
1: SnCl2, HCl 2: NaOH / H2O; methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 5 p. 627 - 629
反应条件
1: 70percent HNO3, HOAc 2: SnCl2, HCl 3: NaOH / H2O; methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 5 p. 627 - 629
反应条件
in tetrahydrofuran T=20°C; 2 h;
参考文献
Palanki, Moorthy S. S.; Erdman, Paul E.; Ren, Minghuan; Suto, Mark; Bennett, Brydon L.; Manning, Anthony; Ransone, Lynn; Spooner, Cheryl; Desai, Sonal; Ow, Arnie; Totsuka, Ryuichi; Tsao, Peter; Toriumi, Wataru
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 4077 - 4080
反应条件
1.1: 4 h / Heating 1.2: aq. NH3 / 4 h / 20 °C 1.3: 99.1 percent / aq. NaOH / 0.5 h / Heating 2.1: 90.6 percent / SOCl2 / 2 h / Heating View Scheme
参考文献
Rocco, Silvana A.; Barbarini, Jose Eduardo; Rittner, Roberto
Synthesis, 2004 , # 3 p. 429 - 435
反应条件
1: HOAc / H2O 2: 85 percent / POCl3, PhNMe2 3: NaOH / tetrahydrofuran; H2O View Scheme
参考文献
DeRuiter; Brubaker; Millen; Riley
Journal of Medicinal Chemistry, 1986 , vol. 29, # 5 p. 627 - 629
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / -10 - 20 °C / Inert atmosphere 2: manganese(IV) oxide / dichloromethane / 20 °C View Scheme
参考文献
Patil, Nitin T.; Raut, Vivek S.; Shinde, Valmik S.; Gayatri, Gaddamanugu; Sastry, G. Narahari
Chemistry - A European Journal, 2012 , vol. 18, # 18 p. 5530 - 5535
反应条件
1: 20 percent / 2 h / 170 °C 2: 57 percent / POCl3, dimethylaniline / toluene / 4 h / Heating 3: 2.) aq. satd. Na2CO3 / ethanol / 0.5 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 4, # 8 p. 1203 - 1207
