5-氟吲哚-2-酮合成路线

参考文献

Manley, Jerad M.; Kalman, Monica J.; Conway, Brian G.; Ball, Cynthia C.; Havens, Jeffrey L.; Vaidyanathan, Rajappa
Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6447 - 6450

56341-41-45-氟吲哚-2-酮

557795-19-4舒尼替尼

参考文献

SCINOPHARM (KUNSHAN) BIOCHEMICAL TECHNOLOGY CO., LTD.; HENSCHKE, Julian, P.; CHEN, Yung-Fa
Patent: WO2012/58780 A1, 2012 ;

56341-41-45-氟吲哚-2-酮

443-69-65-氟靛红

参考文献

Rossiter, Sharon
Tetrahedron Letters, 2002 , vol. 43, # 26 p. 4671 - 4673

56341-41-45-氟吲哚-2-酮

2343-22-85-氟吲哚啉

参考文献

Zakrzewska; Kolehmainen; Osmialowski; Gawinecki
Journal of Fluorine Chemistry, 2001 , vol. 111, # 1 p. 1 - 10

56341-41-45-氟吲哚-2-酮+

118753-70-1N,N-双(2-氯乙基)氨基甲酸叔丁酯

866028-06-01’-BOC-5-氟-1,2-二氢-2-氧代-螺[3H-吲哚-3,4’-哌啶]

参考文献

PFIZER JAPAN INC.; HASHIZUME, Yoshinobu; PFIZER INC.
Patent: WO2005/92858 A2, 2005 ;
Location in patent: Page/Page column 60 ;
WO 2005/092858 A2

56341-41-45-氟吲哚-2-酮+

106-93-4二溴乙烷

769965-95-9

参考文献

NOVARTIS AG; ATKINSON, Benjamin; BEATTIE, David; CULSHAW, Andrew James; DALE, James; DEVEREUX, Nicholas James; MCKENNA, Jeffrey
Patent: WO2011/92293 A2, 2011 ;
Location in patent: Page/Page column 85 ;
WO 2011/092293 A1

56341-41-45-氟吲哚-2-酮+

74-88-4甲基碘

866209-99-63,3-二甲基-5-氟氧化吲哚

参考文献

Vu, An T.; Cohn, Stephen T.; Zhang, Puwen; Kim, Callain Y.; Mahaney, Paige E.; Bray, Jenifer A.; Johnston, Grace H.; Koury, Elizabeth J.; Cosmi, Scott A.; Deecher, Darlene C.; Smith, Valerie A.; Harrison, James E.; Leventhal, Liza; Whiteside, Garth T.; Kennedy, Jeffrey D.; Trybulski, Eugene J.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 2051 - 2062

56341-41-45-氟吲哚-2-酮

945381-62-47-氨基-5-氟吲哚啉-2-酮

参考文献

Tang, Peng Cho; Su, Yidong; Zhang, Lei; Xiao, Lu
Patent: US2010/4239 A1, 2010 ;
Location in patent: Page/Page column 56-57 ;

56341-41-45-氟吲哚-2-酮

442883-73-05-氟-3-亚甲基-1,3-二氢-2H-吲哚-2-酮

参考文献

Rossiter, Sharon
Tetrahedron Letters, 2002 , vol. 43, # 26 p. 4671 - 4673