2',5-二氯-2-(甲基氨基)二苯甲酮合成路线 （共 5 条）
反应条件
sodium hydroxide; tetrabutylammomium bromide in tetrahydrofuran
T=60°C; 1 h;
参考文献
Mouzin, Gilbert; Cousse, Henri; Autin, Jean-Marie
Synthesis, 1981 , # 6 p. 448 - 449
反应条件
potassium hydroxide in N,N-dimethyl-formamide
Ambient temperature;
参考文献
Hirai, Kentaro; Ishiba, Teruyuki; Fujishita, Toshio; Sugimoto, Hirohiko
Heterocycles, 1980 , vol. 14, # 5 p. 635 - 638
反应条件
in chloroform
10 h; Ambient temperature;
参考文献
Konwar, D.; Boruah, R. C.; Sandhu, J. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 10 p. 975 - 976
反应条件
hydrogenchloride
multistep reaction: acid hydrolysis, photolysis;
参考文献
Schutz; Fitz
Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 3 p. 177 - 183
反应条件
1: 93.7 percent / benzene / 1 h / 70 - 80 °C
2: 90 percent / NH2NH2*H2O / ethanol / Heating
View Scheme
参考文献
Hirai; Ishiba; Sugimoto; Sasakura; Fujishita; Toyoda; Tsukinoki; Joyama; Hatakeyama; Hirose
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 764 - 773
