2-氨基-4,6-二羟基嘧啶合成路线 （共 7 条）
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate T=5 - 10°C; 2: 2-amino-4,6-dihydroxy-pyrimidine CoolingReflux; 3: With water
参考文献
Wainwright, Philip; Maddaford, Adrian; Simms, Michael; Forrest, Neil; Glen, Rebecca; Hart, James; Zhang, Xiurong; Pryde, David C.; Stephenson, Peter T.; Middleton, Donald S.; Guyot, Thierry; Sutton, Scott C.
Synlett, 2011 , # 13 p. 1900 - 1904
反应条件
trichlorophosphate 1.) reflux, 1.5 h, 2.) RT, 12 h;
参考文献
Seela, Frank; Steker, Herbert
Heterocycles, 1985 , vol. 23, # 10 p. 2521 - 2524
反应条件
trichlorophosphate in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; N,N-dimethyl-formamide
参考文献
Epoch Biosciences, Inc.
Patent: US2003/78413 A1, 2003 ;
反应条件
trichlorophosphate 5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 41 - 44
反应条件
sulfuric acid; potassium nitrate T=20°C; 2 h;
参考文献
Lopez, Sergio; McCabe, Thomas; Stanley McElhinney; McMurry, T. Brian H.; Rozas, Isabel
Tetrahedron Letters, 2009 , vol. 50, # 44 p. 6022 - 6024
反应条件
trichlorophosphate T=100 - 110°C; 6 h;
参考文献
Aoyagi; Yanada; Bessho; Yoneda; Armarego
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 6 p. 1537 - 1539
反应条件
N,N-dimethyl-aniline; trichlorophosphate T=60°C; 1 h; Inert atmosphere;
参考文献
Kuykendall, Darrell W.; Anderson, Cyrus A.; Zimmerman, Steven C.
Organic Letters, 2009 , vol. 11, # 1 p. 61 - 64
