2-氨基-4,6-二氯嘧啶合成路线

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Kuykendall, Darrell W.; Anderson, Cyrus A.; Zimmerman, Steven C.
Organic Letters, 2009 , vol. 11, # 1 p. 61 - 64

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Buettner
Chemische Berichte, 1903 , vol. 36, p. 2234
Full Text Show Details
Gabriel
Chemische Berichte, 1901 , vol. 34, p. 3363

1194-21-42-氨基-6-氯-4-羟基嘧啶

56-05-32-氨基-4,6-二氯嘧啶

参考文献

Savall, Brad M.; Chavez, Frank; Tays, Kevin; Dunford, Paul J.; Cowden, Jeffery M.; Hack, Michael D.; Wolin, Ronald L.; Thurmond, Robin L.; Edwards, James P.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2429 - 2439

4425-67-62-氨基-4,6(1H,5H)-嘧啶二酮

56-05-32-氨基-4,6-二氯嘧啶+

51501-53-22-氨基-4,5,6-三氯嘧啶

参考文献

Childress; McKee
Journal of the American Chemical Society, 1950 , vol. 72, p. 4271
Journal of the American Chemical Society, 1951 , vol. 73, p. 3862

3764-01-02,4,6-三氯嘧啶

56-05-32-氨基-4,6-二氯嘧啶

参考文献

Delia, Thomas J.; Meltsner, Bernard R.; Schomaker, Jennifer M.
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 5 p. 1259 - 1261

3764-01-02,4,6-三氯嘧啶+

7664-41-7氨气

10132-07-74-氨基-2,6-二氯嘧啶+

56-05-32-氨基-4,6-二氯嘧啶

参考文献

Buettner
Chemische Berichte, 1903 , vol. 36, p. 2227
Full Text Show Details
Gabriel
Chemische Berichte, 1901 , vol. 34, p. 3363

56-05-32-氨基-4,6-二氯嘧啶+

71-43-2苯

3740-92-9解草啶

参考文献

Lee, Hong Woo; Bok, Young Kim; Joong, Bok Ahn; Sung, Kwon Kang; Lee, Jung Hwa; Jae, Soo Shin; Soon, Kil Ahn; Lee, Sang Joon; Seung, Soo Yoon
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 9 p. 862 - 874

109-01-3N-甲基哌嗪+

56-05-32-氨基-4,6-二氯嘧啶

322691-38-34-氯-6-(4-甲基哌嗪-1-基)嘧啶-2-胺

参考文献

Altenbach, Robert J.; Adair, Ronald M.; Bettencourt, Brian M.; Black, Lawrence A.; Fix-Stenzel, Shannon R.; Gopalakrishnan, Sujatha M.; Hsieh, Gin C.; Liu, Huaqing; Marsh, Kennan C.; McPherson, Michael J.; Milicic, Ivan; Miller, Thomas R.; Vortherms, Timothy A.; Warrior, Usha; Wetter, Jill M.; Wishart, Neil; Witte, David G.; Honore, Prisca; Esbenshade, Timothy A.; Hancock, Arthur A.; Brioni, Jorge D.; Cowart, Marlon D.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6571 - 6580

56-05-32-氨基-4,6-二氯嘧啶+

98-80-6苯硼酸

36314-97-32-氨基-4-氯-6-苯基嘧啶

参考文献

SCHERING CORPORATION
Patent: WO2009/111449 A1, 2009 ;
Location in patent: Page/Page column 38-39 ;
WO 2009/111449 A1

56-05-32-氨基-4,6-二氯嘧啶+

1679-18-14-氯苯硼酸

215257-64-0

参考文献

Yaziji, Vicente; Rodriguez, David; Gutierrez-De-Teran, Hugo; Coelho, Alberto; Caamano, Olga; Garcia-Mera, Xerardo; Brea, Jose; Loza, Maria Isabel; Cadavid, Maria Isabel; Sotelo, Eddy
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