1-(1,3-苯并二氧代-5-基)哌嗪合成路线 （共 3 条）
反应条件
sodium t-butanolate; palladium diacetate; tri-tert-butyl phosphine in o-xylene
T=120°C; Yield given;
参考文献
Nishiyama, Masakazu; Yamamoto, Toshihide; Koie, Yasuyuki
Tetrahedron Letters, 1998 , vol. 39, # 7 p. 617 - 620
反应条件
sodium carbonate in ethanol
20 h; Heating;
参考文献
Romanelli; Manetti; Scapecchi; Borea; Dei; Bartolini; Ghelardini; Gualtieri; Guandalini; Varani
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3946 - 3955
参考文献
Eisai Co., Ltd.
Patent: EP1382603 A1, 2004 ;
Location in patent: Page 176; 177 ;
