5-叔丁基-3-异氰酰基异噁唑合成路线 （共 5 条）
反应条件
dimethyl amine in benzene
参考文献
Eli Lilly and Company
Patent: US4336056 A1, 1982 ;
反应条件
triethylamine in dichloromethane; toluene
T=-20 - -15°C; 1.5 h;
参考文献
Bhagwat, Shripad; Chao, Qi; Grotzfeld, Robert M.; Patel, Hitesh K.; Sprankle, Kelly G.
Patent: US2007/232604 A1, 2007 ;
Location in patent: Page/Page column 38 ;
反应条件
pyridine in dichloromethane; toluene
T=20°C; 16 h;
参考文献
Bayer Pharmaceuticals Corp.
Patent: EP1047418 B1, 2005 ;
Location in patent: Page/Page column 42 ;
反应条件
in toluene
T=0 - 20°C;
参考文献
AMBIT BIOSCIENCES CORPORATION
Patent: WO2005/48948 A2, 2005 ;
Location in patent: Page/Page column 156 ;
参考文献
PPG Industries, Inc.
Patent: US4268679 A1, 1981 ;
