7-(3-羟基丙氧基)-4(3h)-喹唑啉酮合成路线

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/105764 A1, 2004 ;
Location in patent: Page 42 ;
WO 2004/105764 A1

16499-57-37-氟-4-喹唑啉酮

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

参考文献

WO2004/41829 A1, ;

Page 92 ;
WO 2004/041829 A1

446-32-22-氨基-4-氟苯甲酸

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

参考文献

Chemical Biology and Drug Design, , vol. 81, # 3 p. 399 - 407

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

557770-90-84-氯-7-[3-氯丙氧基]喹唑啉

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/105764 A1, 2004 ;
Location in patent: Page 42-43 ;
WO 2004/105764 A1

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

557770-91-9[5-[7-(3-氯丙氧基)喹唑啉-4-氨基]吡唑-3-基]乙酸

参考文献

Mortlock, Andrew A.; Foote, Kevin M.; Heron, Nicola M.; Jung, Frederic H.; Pasquet, Georges; Lohmann, Jean-Jacques M.; Warin, Nicolas; Renaud, Fabrice; De Savi, Chris; Roberts, Nicola J.; Johnson, Trevor; Dousson, Cyril B.; Hill, George B.; Perkins, David; Hatter, Glenn; Wilkinson, Robert W.; Wedge, Stephen R.; Heaton, Simon P.; Odedra, Rajesh; Keen, Nicholas J.; Crafter, Claire; Brown, Elaine; Thompson, Katherine; Brightwell, Stephen; Khatri, Liz; Brady, Madeleine C.; Kearney, Sarah; McKillop, David; Rhead, Steve; Parry, Tony; Green, Stephen
Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2213 - 2224

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

957881-03-73-[[7-[3-[乙基[2-(磷酰氧基)乙基]氨基]丙氧基]-4-喹唑啉基]氨基]-N-(3-氟苯基)-1H-吡唑-5-乙酰胺

参考文献

Mortlock, Andrew A.; Foote, Kevin M.; Heron, Nicola M.; Jung, Frederic H.; Pasquet, Georges; Lohmann, Jean-Jacques M.; Warin, Nicolas; Renaud, Fabrice; De Savi, Chris; Roberts, Nicola J.; Johnson, Trevor; Dousson, Cyril B.; Hill, George B.; Perkins, David; Hatter, Glenn; Wilkinson, Robert W.; Wedge, Stephen R.; Heaton, Simon P.; Odedra, Rajesh; Keen, Nicholas J.; Crafter, Claire; Brown, Elaine; Thompson, Katherine; Brightwell, Stephen; Khatri, Liz; Brady, Madeleine C.; Kearney, Sarah; McKillop, David; Rhead, Steve; Parry, Tony; Green, Stephen
Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2213 - 2224

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

722544-51-6Barasertib

参考文献

Mortlock, Andrew A.; Foote, Kevin M.; Heron, Nicola M.; Jung, Frederic H.; Pasquet, Georges; Lohmann, Jean-Jacques M.; Warin, Nicolas; Renaud, Fabrice; De Savi, Chris; Roberts, Nicola J.; Johnson, Trevor; Dousson, Cyril B.; Hill, George B.; Perkins, David; Hatter, Glenn; Wilkinson, Robert W.; Wedge, Stephen R.; Heaton, Simon P.; Odedra, Rajesh; Keen, Nicholas J.; Crafter, Claire; Brown, Elaine; Thompson, Katherine; Brightwell, Stephen; Khatri, Liz; Brady, Madeleine C.; Kearney, Sarah; McKillop, David; Rhead, Steve; Parry, Tony; Green, Stephen
Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2213 - 2224

557770-89-57-(3-羟基丙氧基)-4(3h)-喹唑啉酮

957881-03-73-[[7-[3-[乙基[2-(磷酰氧基)乙基]氨基]丙氧基]-4-喹唑啉基]氨基]-N-(3-氟苯基)-1H-吡唑-5-乙酰胺

参考文献

Mortlock, Andrew A.; Foote, Kevin M.; Heron, Nicola M.; Jung, Frederic H.; Pasquet, Georges; Lohmann, Jean-Jacques M.; Warin, Nicolas; Renaud, Fabrice; De Savi, Chris; Roberts, Nicola J.; Johnson, Trevor; Dousson, Cyril B.; Hill, George B.; Perkins, David; Hatter, Glenn; Wilkinson, Robert W.; Wedge, Stephen R.; Heaton, Simon P.; Odedra, Rajesh; Keen, Nicholas J.; Crafter, Claire; Brown, Elaine; Thompson, Katherine; Brightwell, Stephen; Khatri, Liz; Brady, Madeleine C.; Kearney, Sarah; McKillop, David; Rhead, Steve; Parry, Tony; Green, Stephen
Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2213 - 2224