1-(2,2,4-三甲基-3-环己烯-1-基)乙烷-1-酮合成路线 （共 5 条）
反应条件
1: methyl vinyl ketone With AlCl3, aluminium chloride in tetrahydrofuran
T=5 - 20°C;
2: 2,4-Dimethyl-1,3-pentadiene in tetrahydrofuran
T=15 - 45°C; Diels-Alder Reaction; 19.5 h;
参考文献
SYNGENTA PARTICIPATIONS AG; STIERLI, Daniel; WALTER, Harald
Patent: WO2011/101256 A1, 2011 ;
Location in patent: Page/Page column 19-20 ;
反应条件
ethylaluminum dichloride in benzene
T=0°C; 0.416667 h;
参考文献
Fujiwara, Tooru; Takeda, Takeshi
Tetrahedron Letters, 1990 , vol. 31, # 42 p. 6027 - 6030
反应条件
1: 1) CuI / 1) THF, 40 min, -40 deg C or 30 min, -20 deg C 2) 30 min, -20 deg C
2: 67 percent / EtAlCl2 / benzene / 0.42 h / 0 °C
View Scheme
参考文献
Fujiwara, Tooru; Takeda, Takeshi
Tetrahedron Letters, 1990 , vol. 31, # 42 p. 6027 - 6030
反应条件
sodium dichromate; sulfuric acid
参考文献
Jitkow; Bogert
Journal of the American Chemical Society, 1941 , vol. 63, p. 1979,1984
反应条件
2: 550 °C
View Scheme
参考文献
Cant,P.A.E. et al.
Australian Journal of Chemistry, 1975 , vol. 28, p. 621 - 630
