7-甲氧基-3,4-二氢喹噁啉-2(1h)-酮合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in water
T=60°C; P=2844.39 Torr; Product distribution / selectivity;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/71961 A1, 2008 ;
Location in patent: Page/Page column 92 ;
WO 2008/071961 A1
反应条件
hydrogen; palladium 10 on activated carbon in methanol; acetic acid
Product distribution / selectivity;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/71981 A1, 2008 ;
Location in patent: Page/Page column 51 ;
WO 2008/071981 A1
反应条件
hydrogen; palladium 10 on activated carbon in methanol; acetic acid
T=20°C; Product distribution / selectivity;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/71961 A1, 2008 ;
Location in patent: Page/Page column 92 ;
WO 2008/071961 A1
反应条件
ethanol; nickel
T=60°C; P=44130.5 Torr; Hydrogenation;
参考文献
Curd; Davey; Stacey
Journal of the Chemical Society, 1949 , p. 1271,1275
反应条件
1: xylene
2: Raney nickel; ethanol / 60 °C / 44130.5 Torr / Hydrogenation
View Scheme
参考文献
Curd; Davey; Stacey
Journal of the Chemical Society, 1949 , p. 1271,1275
反应条件
1: potassium carbonate / 4 h / 150 °C
2: iron / acetic acid / 4 h / 90 °C
View Scheme
参考文献
VITAS PHARMA RESEARCH PVT LTD; ALAPATI, Chandrasekhar; BANERJEE, Ankita; RANGARAJAN, Radha; KUMAR, Rajinder
Patent: WO2014/57415 A2, 2014 ;
反应条件
1: aqueous ammoniacal AgNO3
2: POCl3
View Scheme
参考文献
Curd; Davey; Stacey
Journal of the Chemical Society, 1949 , p. 1271,1275
