叔丁氧羰基-苯丙氨酰-丙氨酸合成路线 （共 8 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; 1 h;
参考文献
Fustero, Santos; Sancho, Amador Garcia; Chiva, Gema; Sanz-Cervera, Juan F.; Del Pozo, Carlos; Acena, Jose Luis
Journal of Organic Chemistry, 2006 , vol. 71, # 8 p. 3299 - 3302
反应条件
triethylamine in water; acetonitrile
T=20°C;
参考文献
Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K.
Synthesis, 2004 , # 16 p. 2645 - 2652
反应条件
sodium hydrogencarbonate in ethanol; water; acetone
T=20°C; 5 h;
参考文献
Popovic, Stanimir; Bieraeugel, Hans; Detz, Remko J.; Kluwer, Alexander M.; Koole, Jelmer A. A.; Streefkerk, Dieuwertje E.; Hiemstra, Henk; Van Maarseveen, Jan H.
Chemistry - A European Journal, 2013 , vol. 19, # 50 p. 16934 - 16937
反应条件
sodium hydroxide in water; N,N-dimethyl-formamide
0.25 h;
参考文献
Martinez, Jean; Laur, Janine; Castro, Bertrand
Tetrahedron, 1985 , vol. 41, # 4 p. 739 - 744
反应条件
1: ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate, Et3N / CH2Cl2 / 4 h / Ambient temperature
2: 82 percent / aq. sodium phosphate buffer, lipase N (Amano) / acetone / 37 °C
View Scheme
参考文献
Gewehr, Markus; Kunz, Horst
Synthesis, 1997 , # 12 p. 1499 - 1510
反应条件
tetra(n-butyl)ammonium hydroxide in water; dimethyl sulfoxide
T=0°C; 0.5 h;
参考文献
Verardo; Gorassini
Journal of Peptide Science, 2013 , vol. 19, # 5 p. 315 - 324
反应条件
sodium hydroxide in tetrahydrofuran; water
T=0 - 23°C;
参考文献
Zajdlik, Adam; Wang, Zezhou; Hickey, Jennifer L.; Aman, Ahmed; Schimmer, Aaron D.; Yudin, Andrei K.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8411 - 8415
Angew. Chem., 2013 , vol. 125, # 32 p. 8569 - 8573
反应条件
HOBt-6-carboxamidomethyl polystyrene; dicyclohexyl-carbodiimide
1.) CH2Cl2, RT, 6 h, 2.) CHCl3, RT, 5 h; Yield given. Multistep reaction;
参考文献
Chen, Shui-Tein; Chang, Chung-Ho; Wang, Kung-Tsung
Journal of Chemical Research, Miniprint, 1991 , # 8 p. 1967 - 1975
