2-异丙基-2-苯基乙腈合成路线 （共 22 条）
反应条件
potassium hydroxide; tetrabutylammomium bromide T=45°C; 3.5 h;
参考文献
Barbasiewicz, Michal; Marciniak, Karolina; Fedorynski, Michal
Tetrahedron Letters, 2006 , vol. 47, # 23 p. 3871 - 3874
反应条件
sodium amide in toluene; benzene T=80°C; 1 h;
参考文献
Hartmann, Rolf W.; Batzl, Christine
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1362 - 1369
反应条件
sodium cyanide; N-benzyl-N,N,N-triethylammonium chloride in acetonitrile T=40°C; 80 h;
参考文献
Singh, N. P.; Kumar, A.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 1195 - 1196
反应条件
sodium amide anschliessend Reaktion mit Isopropylbromid;
参考文献
Journal of the American Chemical Society, , vol. 77, p. 369,371
反应条件
sodium hydroxide in dichloromethane T=20°C; 20 h;
参考文献
Badet, Bernard; Julia, Marc; Lefebvre, Christian
Bulletin de la Societe Chimique de France, 1984 , vol. 2, # 11-12 p. 431 - 434
反应条件
potassium hydroxide in ethylene glycol
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 121 - 124
反应条件
1.1: copper (I) cyanide / tetrahydrofuran; hexane; diethyl ether / 0.17 h / -30 - -10 °C / |Inert atmosphere 1.2: 0.33 h / -30 °C / |Inert atmosphere 1.3: -30 °C / |Inert atmosphere 2.1: dicyclohexyl-carbodiimide; pyridine; triethylamine / tetrahydrofuran; hexane; diethyl ether; dichloromethane / 12 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Synthesis (Germany), , vol. 44, # 18 p. 2933 - 2937
反应条件
copper(l) iodide; sodium hydride 1.) HMPA, room temperature, 0.5 h, 2.) 170 deg C, 5 h, then 200 deg C, overnight; Yield given. Multistep reaction;
参考文献
Chemistry Letters, , p. 1779 - 1780
参考文献
Justus Liebigs Annalen der Chemie, , p. 1964 - 1971
反应条件
(i) nBuLi, N-isopropylcyclohexylamine, THF, hexane, (ii) /BRN= 741852/; Multistep reaction;
参考文献
Tetrahedron Letters, , p. 707 - 710
