2-氨基-N-苯基乙酰胺合成路线 （共 22 条）
参考文献
Sumitomo Chemical Company, Limited
Patent: US4755215 A1, 1988 ;
反应条件
1: absolute alcohol 2: mercury (II)-chloride; water View Scheme
参考文献
Johnson; Hill; Kelsey
Journal of the American Chemical Society, 1920 , vol. 42, p. 1714,1719
反应条件
potassium carbonate in chloroform 4 h;
参考文献
Matsuura, Izumi; Ueda, Taisei; Murakami, Nobutoshi; Nagai, Shin-ichi; Sakakibara, Jinsaku
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 11 p. 2821 - 2826
反应条件
1: With hydrogenchloride in 1,4-dioxane
4 h; Cooling with ice;
2: With sodium hydroxide in water
pH=11;
参考文献
TAKASAGO INTERNATIONAL CORPORATION
Patent: US2012/136176 A1, 2012 ;
Location in patent: Page/Page column 11-12; 23 ;
反应条件
10 Pd/C; hydrogen in ethyl acetate
P=2280.15 Torr;
参考文献
Dosa, Stefan; Stirnberg, Marit; Luelsdorff, Verena; Haeussler, Daniela; Maurer, Eva; Guetschow, Michael
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6489 - 6505,17
反应条件
3.5 Pd/C; hydrogen in methanol
Autoclave;
参考文献
Chen, Xiufu; Wang, Jingyun; Cui, Jingnan; Xu, Zhaochao; Peng, Xiaojun
Tetrahedron, 2011 , vol. 67, # 26 p. 4869 - 4873
反应条件
ethanol; ammonia
T=20°C;
参考文献
Abderhalden; Brockmann
Fermentforschung, vol. 10, p. 164
Chem. Zentralbl., 1929 , vol. 100, # I p. 2314
Full Text Show Details
Hill; Kelsey
Journal of the American Chemical Society, 1920 , vol. 42, p. 1707
反应条件
hydrazine in ethanol
2 h; Reflux;
参考文献
Verghese, Jenson; Nguyen, Thuy; Oppegard, Lisa M.; Seivert, Lauren M.; Hiasa, Hiroshi; Ellis, Keith C.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 21 p. 5874 - 5877
反应条件
1: 1.) N,N'-carbonyldiimidazole / 1.) THF, 0 deg C, 1 h, 2.) from 0 deg C to RT, overnight
2: TFA / 0.83 h / 0 °C
View Scheme
参考文献
Nakane, Masami; Reid, Joyce A.; Han, Wen-Ching; Das, Jagabandhu; Truc, Vu Chi; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 9 p. 2465 - 2476
反应条件
ethanol; hydrazine hydrate
参考文献
Sheehan; Frank
Journal of the American Chemical Society, 1949 , vol. 71, p. 1856,1860
