Cbz-L-天门冬氨酸 4-叔丁酯合成路线 （共 37 条）
反应条件
Alcalase-cross-linked-enzyme-aggregates in tert-butyl alcohol T=37°C; pH=7.5; 16 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Nuijens, Timo; Kruijtzer, John A.W.; Cusan, Claudia; Rijkers, Dirk T.S.; Liskamp, Rob M.J.; Quaedflieg, Peter J.L.M.
Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2719 - 2721
反应条件
sodium hydroxide in ethanol
参考文献
Chevallet, Pierre; Garrouste, Patrick; Malawska, Barbara; Martinez, Jean
Tetrahedron Letters, 1993 , vol. 34, # 46 p. 7409 - 7412
反应条件
sulfuric acid T=20°C; 5.5 h; Product distribution / selectivity;
参考文献
Allen, David Robert; Kyung-Lee, Seung-Hee
Patent: US2003/236430 A1, 2003 ;
Location in patent: Page 3 ;
反应条件
1: H2 / Pd-C / aq. ethanol 2: aq. NaOH View Scheme
参考文献
Journal of Organic Chemistry, , vol. 28, p. 1251 - 1253
反应条件
triethylamine in dichloromethane T=0°C;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
titanium(IV) isopropylate T=20 - 50°C; 6.5 - 15 h; Product distribution / selectivity;
参考文献
US2003/236430 A1, ;
Page 3 ;
反应条件
boron trifluoride diethyl etherate T=20°C; 5 h; Product distribution / selectivity;
参考文献
US2003/236430 A1, ;
Page column 4 ;
反应条件
1: 82 percent / benzyltriethylammonium chloride, K2CO3 / N,N-dimethyl-acetamide / 24 h / 55 °C 2: 80 percent / 1 N NaOH / ethanol View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 46 p. 7409 - 7412
反应条件
1: dicyclohexylamine 2: H2SO4 3: aq. NaOH / acetone View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 673, p. 208 - 220
反应条件
boron trifluoride diethyl etherate T=20°C; 5 h; Product distribution / selectivity;
参考文献
Allen, David Robert; Kyung-Lee, Seung-Hee
Patent: US2003/236430 A1, 2003 ;
Location in patent: Page column 4 ;
