4-(2-氨基乙基)-2-甲氧基苯酚合成路线 （共 34 条）
反应条件
sulfuric acid; hydrogen; palladium on activated carbon in methanol T=20 - 25°C; P=3750.38 Torr; 4.33333 h;
参考文献
SYNGENTA PARTICIPATIONS AG
Patent: WO2007/20381 A2, 2007 ;
Location in patent: Page/Page column 16; 30 ;
反应条件
hydrogen; Ra-Ni in ethanol; ammonia T=70°C; P=6080 - 7600 Torr;
参考文献
Szantay; Dornyei; Blasko; et al.
Archiv der Pharmazie, 1981 , vol. 314, # 12 p. 983 - 991
反应条件
ammonium hydroxide in water T=50°C; pH=9 - 10;
参考文献
MILLER, James Jackson; PHILLIPS, Anthony George; LAPISH, Christopher Court; SAMMIS, Glenn Martin
Patent: WO2013/20229 A1, 2013 ;
Location in patent: Paragraph 0193 ;
WO 2013/020229 A1
反应条件
diisobutylaluminium hydride in 1,4-dioxane T=60°C;
参考文献
Vinogradova, V. I.; Yunusov, M. S.; Kuchin, A. V.; Tolstikov, G. A.; Sagandykov, R. T.; et al.
Chemistry of Natural Compounds, 1990 , vol. 26, # 1 p. 54 - 59
Khimiya Prirodnykh Soedinenii, 1990 , # 1 p. 67 - 74
反应条件
palladium on charcoal in tetrahydrofuran
反应条件
1: 75 percent / NH4(OAc) / acetic acid / Heating 2: 25 percent / DIBAH / dioxane / 60 °C View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 26, # 1 p. 54 - 59
Khimiya Prirodnykh Soedinenii, , # 1 p. 67 - 74
反应条件
palladium on activated charcoal; ethanol Hydrogenation.unter Zusatz von wenig konz.wss.HCl;
参考文献
Journal of Biological Chemistry, , vol. 233, p. 697
反应条件
1.1: AlCl3 / toluene 1.2: Br2; AcOH / CH2Cl2 / -78 °C 2.1: 75 percent / NH3; H2 / Ra-Ni catalyst / ethanol / 70 °C / 7600 Torr View Scheme
参考文献
Synthesis, , # 8 p. 1375 - 1385
反应条件
1: dimethylformamide 2: H2, aq. HCl / Pd-C / ethanol View Scheme
参考文献
Tetrahedron, , vol. 29, p. 1931 - 1939
参考文献
Yakugaku Zasshi, , vol. 79, p. 1331,1333
Chem.Abstr., , p. 3299
Acta Chimica Academiae Scientiarum Hungaricae, , vol. 14, p. 325,328
Journal of the American Chemical Society, , vol. 75, p. 5119
