2,5-二氢-1-甲基-1H-吡咯合成路线 (共 11 条)
反应条件
1: With triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride
T=85°C; P=5250.53 Torr; 10 h;
2: With hydrogenchloride
T=25 - 30°C; 0.5 h; aqueous solution;
3: With hydrogenchloride in dichloromethane
T=25 - 30°C; 0.5 h;
参考文献
ASTRAZENECA AB
Patent: WO2004/792 A1, 2003 ;
Location in patent: Page 24 ;