2-甲基-4-(4-吡啶)-3-丁炔-2-醇合成路线 （共 5 条）
反应条件
sodium hydroxide in toluene 2 h; Heating;
参考文献
Ciana, Leopoldo Della; Haim, Albert
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 607 - 608
反应条件
copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; diethylamine
T=20°C; 4.5 h;
参考文献
Yu; Lindsey
Journal of Organic Chemistry, 2001 , vol. 66, # 22 p. 7402 - 7419
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-ethyl-N,N-diisopropylamine in water
T=69.84°C; Inert atmosphereDarkness;
参考文献
Munoz-Lara, Francisco J.; Gaspar, Ana B.; Munoz, M. Carmen; Ksenofontov, Vadim; Real, Jose Antonio
Inorganic Chemistry, 2013 , vol. 52, # 1 p. 3 - 5
反应条件
copper(l) iodide; (C6H5)3Pd(II)Cl; diethylamine in acetonitrile
参考文献
Kalgutkar, Amit S.; Castagnoli, Neal
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4165 - 4174
反应条件
1: KOH / toluene / 0.75 h / Heating
2: 25 mg / CuI, Et2NH / bis(triphenylphosphine)palladium(II) chloride / toluene / 15 h / Ambient temperature
View Scheme
参考文献
Anderson, Harry L.; Walter, Christopher J.; Vidal-Ferran, Anton; Hay, Robert A.; Lowden, Philip A.; Sanders, Jeremy K. M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 18 p. 2275 - 2280
