6-(4-甲氧基苯基)-6-氧代己酸合成路线 （共 16 条）
反应条件
sodium hydroxide in tetrahydrofuran Ambient temperature;
参考文献
Kogan, Timothy P.; Dupre, Brian; Bui, Huong; McAbee, Kathy L.; Kassir, Jamal M.; Scott, Ian L.; Hu, Xin; Vanderslice, Peter; Beck, Pamela J.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1099 - 1111
反应条件
aluminium trichloride; tetrachloroethane, 1,1,2,2- Behandeln des Reaktionsprodukts mit aethanol. bzw. wss. Natronlauge;
参考文献
Journal of the American Chemical Society, , vol. 69, p. 3018,3021
Journal of Organic Chemistry, , vol. 13, p. 576,578
反应条件
jones reagent in acetone 1 h;
参考文献
Australian Journal of Chemistry, , vol. 36, # 2 p. 361 - 370
反应条件
1: AlCl3 / CH2Cl2 / 0.5 h / 0 °C 2: 87 percent / 2N aq. NaOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 7 p. 1099 - 1111
反应条件
1: thionyl chloride / 0.5 h / 80 °C 2: AlCl3 / CH2Cl2 / 0.5 h / 0 °C 3: 87 percent / 2N aq. NaOH / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 7 p. 1099 - 1111
反应条件
chromium(VI) oxide; acetic acid
参考文献
Journal of the American Chemical Society, , vol. 70, p. 3352,3354
反应条件
carbon disulfide; aluminium trichloride
参考文献
Journal of the American Chemical Society, , vol. 53, p. 4187,4191
反应条件
potassium hydroxide in tetrahydrofuran; ethanol
参考文献
Tetrahedron, , vol. 29, p. 2183 - 2188
反应条件
1: 1.) sodium borohydride, boron trifluoride etherate, 2.) 2 M aq. NaOH, 30percent aq. H2O2 / 1.) diglyme, THF, 3.5 h, 2.) diglyme, THF, ethanol, reflux, 1.7 h 2: 0.95 g / Jones reagent / acetone / 1 h View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 2 p. 361 - 370
反应条件
1: 56 percent / diethyl ether 2: 1.) sodium borohydride, boron trifluoride etherate, 2.) 2 M aq. NaOH, 30percent aq. H2O2 / 1.) diglyme, THF, 3.5 h, 2.) diglyme, THF, ethanol, reflux, 1.7 h 3: 0.95 g / Jones reagent / acetone / 1 h View Scheme
参考文献
Australian Journal of Chemistry, , vol. 36, # 2 p. 361 - 370
