4-(2,3-环氧基丙基氧基)甲基苯甲酸合成路线 （共 4 条）
反应条件
1: With water; sodium hydroxide in acetone T=20°C; 2 h; 2: in water pH=4; Cooling with iceAcidic conditions;
参考文献
Cheedarala, Ravi Kumar; Sunkara, Vijaya; Park, Joon Won
Synthetic Communications, 2009 , vol. 39, # 11 p. 1966 - 1980
反应条件
potassium carbonate in acetone
T=120°C; 0.25 h; Microwave irradiationSealed tube;
参考文献
Schmitt, Martin L.; Hauser, Alexander-Thomas; Carlino, Luca; Pippel, Martin; Schulz-Fincke, Johannes; Metzger, Eric; Willmann, Dominica; Yiu, Teresa; Barton, Michelle; Schuele, Roland; Sippl, Wolfgang; Jung, Manfred
Journal of Medicinal Chemistry, 2013 , vol. 56, # 18 p. 7334 - 7342
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=70°C;
参考文献
Ohno, Tomoyasu; Ogawa, Kazuo; Yano, Shingo; Fukushima, Masakazu; Suzuki, Norihiko; Asao, Tetsuji
Archiv der Pharmazie, 2005 , vol. 338, # 4 p. 147 - 158
反应条件
1: conc. H2SO4, 3A molecular sieves / 72 h / Heating
2: K2CO3 / acetone / 20 h / Heating
View Scheme
参考文献
Erhardt, Paul W.; Woo, Chi M.; Anderson, William G.; Gorczynski, Richard J.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 12 p. 1408 - 1412
