3-(4-甲氧基苯基)-1H-吲唑合成路线 （共 12 条）
反应条件
N-benzyl-N,N,N-triethylammonium chloride; cesium fluoride in tetrahydrofuran
T=70°C; 24 h;
参考文献
Li, Pan; Wu, Chunrui; Zhao, Jingjing; Rogness, Donald C.; Shi, Feng
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3149 - 3158
反应条件
sodium carbonate; tetrakis (triphenylphosphine) palladium (0) in ethylene glycol dimethyl ether
参考文献
Bhagwat, Shripad S.; Satoh, Yoshitaka; Sakata, Steven T.; Buhr, Chris A.; Albers, Ronald; Sapienza, John; Plantevin, Veronique; Chao, Qi; Sahasrabudhe, Kiran; Ferri, Rachel
Patent: US2002/103229 A1, 2002 ;
US 20020103229 A1
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in 1,4-dioxane; water
T=120°C; Suzuki-Miyaura Coupling; 1 h; Microwave irradiation;
参考文献
Youngsaye, Willmen; Hartland, Cathy L.; Morgan, Barbara J.; Ting, Amal; Nag, Partha P.; Vincent, Benjamin; Mosher, Carrie A.; Bittker, Joshua A.; Dandapani, Sivaraman; Palmer, Michelle; Whitesell, Luke; Lindquist, Susan; Schreiber, Stuart L.; Munoz, Benito
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1501 - 1507
反应条件
N-benzyl-N,N,N-triethylammonium chloride; cesium fluoride in tetrahydrofuran
T=70°C; 36 h;
参考文献
Kovacs, Szabolcs; Csincsi, Adam I.; Nagy, Tibor Zs.; Boros, Sandor; Timari, Geza; Novak, Zoltan
Organic Letters, 2012 , vol. 14, # 8 p. 2022 - 2025
反应条件
cesium fluoride in tetrahydrofuran
T=90°C; 24 h;
参考文献
Li, Pan; Zhao, Jingjing; Wu, Chunrui; Larock, Richard C.; Shi, Feng
Organic Letters, 2011 , vol. 13, # 13 p. 3340 - 3343
反应条件
1: methanol / 2 h / 20 °C
2: N-benzyl-N,N,N-triethylammonium chloride; cesium fluoride / tetrahydrofuran / 24 h / 70 °C
View Scheme
参考文献
Li, Pan; Zhao, Jingjing; Wu, Chunrui; Larock, Richard C.; Shi, Feng
Organic Letters, 2011 , vol. 13, # 13 p. 3340 - 3343
反应条件
in diethyl ether; toluene
T=120°C; 18 h; Inert atmosphere;
参考文献
Yu, Da-Gang; Suri, Mamta; Glorius, Frank
Journal of the American Chemical Society, 2013 , vol. 135, # 24 p. 8802 - 8805
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate in ethylene glycol dimethyl ether
T=80°C; 2.5 h;
参考文献
Collot, Valerie; Bovy, Philippe R.; Rault, Sylvain
Tetrahedron Letters, 2000 , vol. 41, # 47 p. 9053 - 9057
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / 20 °C
2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / 1,4-dioxane; water / 1 h / 120 °C / |Microwave irradiation
View Scheme
参考文献
Youngsaye, Willmen; Hartland, Cathy L.; Morgan, Barbara J.; Ting, Amal; Nag, Partha P.; Vincent, Benjamin; Mosher, Carrie A.; Bittker, Joshua A.; Dandapani, Sivaraman; Palmer, Michelle; Whitesell, Luke; Lindquist, Susan; Schreiber, Stuart L.; Munoz, Benito
Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 1501 - 1507
反应条件
1: [{(η5-C5Me5)RhCl}2(μ-Cl)2]; silver hexafluoroantimonate; copper diacetate / 1,2-dichloro-ethane / 24 h / 110 °C / 760.05 Torr / |Inert atmosphere; |Glovebox; |Molecular sieve; |Green chemistry
2: toluene; diethyl ether / 18 h / 120 °C / |Inert atmosphere
View Scheme
参考文献
Yu, Da-Gang; Suri, Mamta; Glorius, Frank
Journal of the American Chemical Society, 2013 , vol. 135, # 24 p. 8802 - 8805
