(4-甲氧基苯基)-甲基苯胺合成路线 （共 16 条）
反应条件
tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in toluene
6 h; Ambient temperature;
参考文献
Topchiy, Maxim A.; Asachenko, Andrey F.; Nechaev, Mikhail S.
European Journal of Organic Chemistry, 2014 , vol. 2014, # 16 p. 3319 - 3322
反应条件
carbon dioxide; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; tris-(dibenzylideneacetone)dipalladium(0)
T=100°C; P=93086.6 Torr; 17 h;
参考文献
Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781
反应条件
sodium t-butanolate; palladium diacetate in toluene
参考文献
Yale University
Patent: US6562989 B2, 2003 ;
反应条件
tris(dibenzylideneacetone)dipalladium (0); di-tert-butylneopentylphosphonium tetrafluoroborate; sodium t-butanolate in toluene
T=100°C; Hartwig-Buchwald amination; 18 h;
参考文献
Hill, Lensey L.; Moore, Lucas R.; Huang, Rongeai; Craciun, Raluca; Vincent, Andrew J.; Dixon, David A.; Chou, Joe; Woltermann, Christopher J.; Shaughnessy, Kevin H.
Journal of Organic Chemistry, 2006 , vol. 71, # 14 p. 5117 - 5125
反应条件
Pd(crotyl)Q-PhosCl; sodium t-butanolate in toluene
T=25°C; Buchwald-Hartwig coupling reaction; 2 h; Inert atmosphere;
参考文献
Seechurn, Carin C.C. Johansson; Parisel, Sebastien L.; Colacot, Thomas J.
Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7918 - 7932
反应条件
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
T=80°C; 16 h;
参考文献
Navarro, Oscar; Kaur, Harneet; Mahjoor, Parisa; Nolan, Steven P.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 3173 - 3180
反应条件
carbon dioxide; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; tris-(dibenzylideneacetone)dipalladium(0)
T=100°C; P=93086.6 Torr; 24 h;
参考文献
Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781
反应条件
palladium diacetate; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; sodium t-butanolate in toluene
T=100°C; 25 h;
参考文献
Kataoka, Noriyasu; Shelby, Quinetta; Stambuli, James P.; Hartwig, John F.
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5553 - 5566
反应条件
carbon dioxide; caesium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; tris-(dibenzylideneacetone)dipalladium(0)
T=100°C; P=93086.6 Torr; 17 h;
参考文献
Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781
反应条件
cesium fluoride in acetonitrile
T=20°C; 5 h;
参考文献
Liu, Zhijian; Larock, Richard C.
Journal of Organic Chemistry, 2006 , vol. 71, # 8 p. 3198 - 3209
