2,7-二氯-1,8-萘啶合成路线 （共 10 条）
反应条件
phosphorus pentachloride; trichlorophosphate 2 h; Heating;
参考文献
Newkome, George R.; Garbis, Sam J.; Majestic, Veronica K.; Fronczek, Frank R.; Chiari, Giacomo
Journal of Organic Chemistry, 1981 , vol. 46, # 5 p. 833 - 839
反应条件
1: With sulfuric acid T=110°C; 3 h; 2: With sulfuric acid; sodium nitrite T=20°C; 0.0833333 h; 3: With phosphorus pentachloride in trichlorophosphate Reflux;
参考文献
Synlett, , vol. 24, # 3 art. no. ST-2012-D1044-L, p. 359 - 362
反应条件
1: 76 percent / 1.) conc. sulfuric acid, sodium nitrite; 2.) Sodium carbonate / 0.25 h / 0 °C 2: 73.8 percent / phosphorus pentachloride, phosphorus trichloride oxide / 3 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Dalton Transactions, , # 23 p. 4561 - 4570
反应条件
1: 97 percent / concentrated sulphuric acid / 3 h / 110 °C 2: 87 percent / concentrated sulfuric acid, sodium nitrite 3: 81 percent / phosphorus pentachloride, phosphorus oxychloride / 2 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 5 p. 833 - 839
反应条件
1: 61 percent / Na / 1 h / Heating 2: 1) conc. H2SO4, sodium nitrite; 2) water / 1) RT, 12 h 3: 89 percent / phosphoryl chloride / 0.17 h / 70 °C / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 2 p. 501 - 504
反应条件
1: 1) conc. H2SO4, sodium nitrite; 2) water / 1) RT, 12 h 2: 89 percent / phosphoryl chloride / 0.17 h / 70 °C / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 23, # 2 p. 501 - 504
反应条件
ammonium hydroxide T=180°C; 24 h;
参考文献
Corbin; Zimmerman; Thiessen; Hawryluk; Murray
Journal of the American Chemical Society, 2001 , vol. 123, # 43 p. 10475 - 10488
反应条件
1: 1.) NaH / 1.) DMF, 2.) DMF, 120 deg C 2: 70 percent / 70percent aq. H2SO4 / 1.5 h / 120 °C View Scheme
参考文献
Mastalarz, H.; Rulko, F.
Polish Journal of Chemistry, 1994 , vol. 68, # 3 p. 459 - 466
参考文献
Ferrarini; Mori; Biagi; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 2 p. 417 - 419
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=20°C; Sonogashira coupling; 40 h;
参考文献
Liao, Jen-Hai; Chen, Chao-Tsen; Chou, He-Chun; Cheng, Chung-Chih; Chou, Pi-Tai; Fang, Jim-Min; Slanina, Zdenek; Chow, Tashin J.
Organic Letters, 2002 , vol. 4, # 18 p. 3107 - 3110
