2-苯基-1,3-丙烷二胺合成路线 （共 9 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
T=20°C; 24 h;
参考文献
Bustos, Eduardo; Gotor-Fernandez, Vicente; Montejo-Bernardo, Jose; Garcia-Granda, Santiago; Gotor, Vicente
Organic Letters, 2007 , vol. 9, # 21 p. 4203 - 4206
反应条件
1: 90 percent / pyridine / 24 h / 20 °C
2: sodium azide / dimethylformamide / 24 h / 55 °C
3: 210 mg / H2 / Pd/C / methanol / 24 h / 20 °C
View Scheme
参考文献
Bustos, Eduardo; Gotor-Fernandez, Vicente; Montejo-Bernardo, Jose; Garcia-Granda, Santiago; Gotor, Vicente
Organic Letters, 2007 , vol. 9, # 21 p. 4203 - 4206
反应条件
1: sodium azide / dimethylformamide / 24 h / 55 °C
2: 210 mg / H2 / Pd/C / methanol / 24 h / 20 °C
View Scheme
参考文献
Bustos, Eduardo; Gotor-Fernandez, Vicente; Montejo-Bernardo, Jose; Garcia-Granda, Santiago; Gotor, Vicente
Organic Letters, 2007 , vol. 9, # 21 p. 4203 - 4206
反应条件
1 Pd/C; hydrogen in methanol
T=20°C; 5 h;
参考文献
Rios-Lombardia, Nicolas; Busto, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente
European Journal of Organic Chemistry, 2010 , # 3 p. 484 - 493
反应条件
sodium hydroxide; bromine
1.) 20 deg C, 1 h, 2.) 70 deg C, 30 min;
参考文献
Weinhardt, Klaus; Wallach, Marshall B.; Marx, Michael
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 694 - 698
参考文献
Nelles
Chemische Berichte, 1932 , vol. 65, p. 1345
反应条件
T=25°C; Kochen mit Bromwasserstoffsaeure;
参考文献
Jackson; Kenner
Journal of the Chemical Society, 1928 , p. 1661
反应条件
in methanol
1 h; Heating;
参考文献
Weinhardt, Klaus; Wallach, Marshall B.; Marx, Michael
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 694 - 698
参考文献
Weinhardt, Klaus; Wallach, Marshall B.; Marx, Michael
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 694 - 698
