4-[(4-甲基-1-哌嗪基)羰基]苯胺合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in methanol 2 h;
参考文献
AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara
Patent: WO2012/59932 A1, 2012 ;
Location in patent: Page/Page column 121 ;
WO 2012/059932 A1
反应条件
1: triethylamine / dichloromethane / 20 °C 2: platinum(IV) oxide; hydrogen / ethanol / 16 h / 2585.81 Torr View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2917 - 2929
反应条件
1: triethylamine; benzotriazol-1-ol; EDC monohydrochloride / N,N-dimethyl-formamide / 12 h / 20 °C 2: methanol / palladium 10 on activated carbon / 3.17 h / 3102.97 Torr / Inert atmosphere View Scheme
反应条件
1: triethylamine / dichloromethane / 3 h / 20 °C 2: methanol / palladium 10 on activated carbon / 3.17 h / 3102.97 Torr / Inert atmosphere View Scheme
反应条件
1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / tetrahydrofuran / 0 °C 2: hydrogen / palladium on activated charcoal / methanol / 2 h View Scheme
参考文献
WO2012/59932 A1, ;
WO 2012/059932 A1
反应条件
1: triethylamine / dichloromethane / 20 °C 2: platinum(IV) oxide; hydrogen / ethanol / 16 h / 2585.81 Torr View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2917 - 2929
反应条件
hydrogenchloride; methanol; platinum Hydrogenation;
参考文献
Journal of Organic Chemistry, , vol. 24, p. 459,460, 461
