1: 88 percent / pyridine / 0 °C 2: Br2 / CH2Cl2 / 2 h 3: KOH / ethanol / 20 h / Heating 4: 50 percent / Et3N / CH2Cl2 / 24 h / Ambient temperature 5: 1.) O3, 2.) Me2S / 1) CH2Cl2, MeOH, -78 deg C; 2) CH2Cl2, MeOH, 4 h 6: 80 percent / immobilized penicillin acylase / ethanol / 0.5 h / 23 °C / pH 7.5 View Scheme

Cp2LaCH(TMS)2 in benzene T=125°C; 36 h;

lithium aluminium tetrahydride; bis(benzonitrile)palladium(II) dichloride; trifluorormethanesulfonic acid; diethylamine Yield given. Multistep reaction. Yields of byproduct given;

bis(benzonitrile)palladium(II) dichloride; trifluorormethanesulfonic acid; hydrogen; diethylamine Yield given. Multistep reaction. Yields of byproduct given;

bis(benzonitrile)palladium(II) dichloride; trifluorormethanesulfonic acid; hydrogen; diethylamine Yield given. Multistep reaction. Yields of byproduct given;

hydrogenchloride; oxygen; sodium chloride; copper dichloride; palladium dichloride in water T=60°C; 6.5 h; Yield given. Yields of byproduct given;