4-甲基-alpha-(4-甲基苯基)苯甲胺合成路线 （共 17 条）
反应条件
in water T=435°C; 1.5 h; supercritical;
参考文献
Hatano, Bunpei; Kadokawa, Jun-Ichi; Tagaya, Hideyuki
Tetrahedron Letters, 2002 , vol. 43, # 33 p. 5859 - 5861
反应条件
in water T=435°C; 1.5 h; supercritical;
参考文献
Tetrahedron Letters, , vol. 43, # 33 p. 5859 - 5861
反应条件
1: in tetrahydrofuran
Inert atmosphereReflux;
2: With lithium aluminium tetrahydride in tetrahydrofuran
T=0°C; Inert atmosphereReflux;
参考文献
Zhang, Yu; Lu, Zhenjie; Desai, Aman; Wulff, William D.
Organic Letters, 2008 , vol. 10, # 23 p. 5429 - 5432
反应条件
sodium tetrahydroborate in methanol
2 h;
参考文献
Dejaegher; Mangelinckx; De Kimpe
Synlett, 2002 , # 1 p. 113 - 115
反应条件
hydrogenchloride; formic acid
T=75°C; Hydrolysis; 0.5 h;
参考文献
Wakamiya, Tateaki; Kamata, Makoto; Kusumoto, Shoichi; Kobayashi, Hiroyuki; Sai, Yoshimichi; Tamai, Ikumi; Tsuji, Akira
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 3 p. 699 - 709
反应条件
hydrogen in methanol
Hydrogenation; P=2250.18 - 3000.24 Torr; 4 h;
参考文献
Sasse; Stark; Ligneau; Elz; Reidemeister; Ganellin; Schwartz; Schunack
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 5 p. 1139 - 1149
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; copper diacetate in 1,4-dioxane
T=70°C; 2 h; Inert atmosphere;
参考文献
Kitamura, Mitsuru; Tokuda, Yu; Tashiro, Norifumi; Okauchi, Tatsuo
Australian Journal of Chemistry, 2012 , vol. 65, # 12 p. 1687 - 1690
反应条件
1: 81 percent / NH2OH*HCl; Na2CO3 / ethanol / 6 h / Heating
2: H2 / methanol / 4 h / 2250.18 - 3000.24 Torr
View Scheme
参考文献
Sasse; Stark; Ligneau; Elz; Reidemeister; Ganellin; Schwartz; Schunack
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 5 p. 1139 - 1149
反应条件
1.1: I2; Mg / tetrahydrofuran / 0.75 h / Heating
1.2: 75 percent / tetrahydrofuran / 5 h / Heating
2.1: 95 percent / NaBH4 / methanol / 2 h
View Scheme
参考文献
Dejaegher; Mangelinckx; De Kimpe
Synlett, 2002 , # 1 p. 113 - 115
反应条件
1.1: I2; Mg / tetrahydrofuran / 0.75 h / Heating
1.2: 75 percent / tetrahydrofuran / 5 h / Heating
2.1: 95 percent / NaBH4 / methanol / 2 h
View Scheme
参考文献
Dejaegher; Mangelinckx; De Kimpe
Synlett, 2002 , # 1 p. 113 - 115
