2,6-二氟苯胺合成路线

289-95-2嘧啶+5509-65-92,6-二氟苯胺→67567-26-44-溴-2,6-二氟苯胺

参考文献

Seiko Epson Corporation
Patent: US5200110 A1, 1993 ;

5509-65-92,6-二氟苯胺→69411-06-94-氯-2,6-二氟苯胺

参考文献

GLENMARK PHARMACEUTICALS S.A.; GHARAT, Laxmikant Atmaram; GAJERA, Jitendra Maganbhai; NARAYANA, Lakshminarayana; KHAIRATKAR-JOSHI, Neelima; KATTIGE, Vidya Ganapati
Patent: WO2012/110860 A1, 2012 ;
Location in patent: Page/Page column 47 ;
WO 2012/110860 A1

→69411-06-94-氯-2,6-二氟苯胺

参考文献

BASF Aktiengesellschaft
Patent: US6624119 B1, 2003 ;

60230-36-62,6-二氟苯磺酰氯+5509-65-92,6-二氟苯胺→60230-37-72,6-二氟苯磺酰胺

参考文献

US6610853 B1, ;

5509-65-92,6-二氟苯胺→64248-56-21-溴-2,6-二氟苯

参考文献

Baik, Woonphil; Luan, Wanqiang; Lee, Hyun Joo; Yoon, Cheol Hun; Koo, Sangho; Kim, Byeong Hyo
Canadian Journal of Chemistry, 2005 , vol. 83, # 3 p. 213 - 219

108-22-5乙酸异丙烯酯+5509-65-92,6-二氟苯胺→101712-20-32,6-双氟苯基丙酮

参考文献

Li, Li; Chen, Hongbiao; Lin, Yuanbin
Synthetic Communications, 2007 , vol. 37, # 6 p. 985 - 991

5509-65-92,6-二氟苯胺→102284-85-5

参考文献

Jin, Li-Mei; Xu, Xue; Lu, Hongjian; Cui, Xin; Wojtas, Lukasz; Zhang, X. Peter
Angewandte Chemie - International Edition, 2013 , vol. 52, # 20 p. 5309 - 5313
Angew. Chem., 2013 , vol. 125, # 20 p. 5417 - 5421,5

5509-65-92,6-二氟苯胺→1033225-44-3N-(2,6-二氟苯基)-1,2-苯二胺

参考文献

Connolly, Terrence J.; Auguscinski, Waldemar; Fung, Peter; Galante, Rocco; Liu, Weiguo; McGovern, Linda; Sebastian, Alice; Shen, Xiaole; Shi, Xinxu; Wilk, Boguslawa; Varsalona, Richard; Zhong, Huijuan
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 868 - 877

5509-65-92,6-二氟苯胺→1033225-43-2N-2-硝基苯基-2,6-二氟苯胺

参考文献

Connolly, Terrence J.; Auguscinski, Waldemar; Fung, Peter; Galante, Rocco; Liu, Weiguo; McGovern, Linda; Sebastian, Alice; Shen, Xiaole; Shi, Xinxu; Wilk, Boguslawa; Varsalona, Richard; Zhong, Huijuan
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 868 - 877

5509-65-92,6-二氟苯胺→103943-13-1

参考文献

Rewcastle; Denny; Baguley
Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 843 - 851